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A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

Certain maturity signs appear before and after the first release of sperm in boys.

Girls with PCOS often start puberty earlier and have signs of insulin resistance from a young age.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

A 46-year-old man showed symptoms of a rare condition usually seen in postmenopausal women, highlighting the need for dentist-dermatologist collaboration.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.

A Chinese man with KID syndrome had a new mutation in the GJB2 gene.

Rural Bangladeshi girls mature later than peers in other low and middle-income countries due to poor nutrition and socioeconomic conditions.

A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Early diagnosis and treatment with Leuprolide are key for children with precocious puberty.

A boy with early puberty and laughing seizures was treated, stopping seizures and slowing puberty.

A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

The document concludes that common menstrual disorders affect adolescent women, with the normal menstrual cycle lasting 21 to 35 days.

A woman with lupus had blood cell destruction, treated successfully with medication.

A teenager's hair with alternating white and dark bands, known as Pili annulati, is a genetic condition that is usually harmless and often considered attractive.

Mother and son diagnosed with a rare genetic hair loss condition with no effective treatment.

Androgens can both increase and decrease hair growth in different parts of the body.

Effective management of children's hair loss involves accurate diagnosis, various treatments, and supportive care.

A 17-year-old developed woolly hair nevus in adolescence, which is unusual, and over time the hair darkened and straightened slightly, but microscopic changes persisted.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

A hair strand caused a rare case of limb strangulation in a teenage girl with autism, and the condition is not always linked to child abuse.

The document concludes that accurate diagnosis of hair loss in children is crucial due to limited treatment options and the condition's psychological impact.

Trichosporon inkin and Trichosporon mucoides can cause white piedra on scalp hair.

After menopause, some women lose scalp hair and gain facial hair, with patterns suggesting different underlying causes.

A person with a specific gene mutation had extra teeth, unique jaw and hair features not seen before in this condition.