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PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Darker skin in 10-year-old girls may be an early sign of puberty.

Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.

A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.

Aging-related hormone changes affect voice quality, especially during puberty, menstruation, pregnancy, and menopause.

PCOS can cause unusual symptoms like late puberty and enlarged clitoris, making diagnosis difficult.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.

A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.

Oestrogens are key for bone growth during puberty in both boys and girls.

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

Higher fluoride levels may delay puberty in boys.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Trichoepitheliomas can be hard to distinguish from other skin conditions and often start in teenage years.

A boy with a rare skin condition improved quickly after starting zinc supplements.

Leptin, a hormone, is important for starting hair growth.

A 10-year-old girl with Fox Fordyce disease improved with treatment, suggesting the disease can occur before puberty and might be underdiagnosed in young girls.

Hair loss, known as androgenic alopecia, can start in teenage years and may not always be hormone-related. It's important to do extra tests in young cases and remember it can greatly affect a teenager's mental health.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

RAPK is a rare skin disorder with pigmented spots, mainly on hands and feet, starting in youth.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Hair and nails can show hormone changes during puberty in dogs.

Understanding hair follicle anatomy helps diagnose hair disorders.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.