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This review discusses medical interventions that reproductive health experts can provide to transgender and gender diverse youth and reports no new clinical results.

This review discusses strategies for maintaining access to gender-affirming care for gender diverse youth during the COVID-19 pandemic and reports no new clinical results.

This article discusses the dermatologic impacts of gender-affirming medical care in transgender adolescents and emphasizes the importance of patient-centered care to improve dermatologic and overall outcomes; it reports no new clinical results.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

This study found that transdermal DHT treatment increased penile length in boys with 5α-reductase type 2 deficiency, but post-pubertal growth was limited and carried potential prostate complications.

In this retrospective study, cyproterone acetate treatment in late-pubertal trans-girls was found to be generally safe and led to mild feminizing effects, with more rapid feminization occurring when combined with estrogens.

This article reviews the diagnosis and management of hirsutism in women, discussing its causes, assessment, and treatment options; no new clinical findings are included.

This review discusses androgenization symptoms like hirsutism, alopecia, and acne in reproductive-age women, focusing on diagnostic and therapeutic approaches, and highlights postmenopausal considerations, but presents no new clinical findings.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.

This article reviews the use of cross-sex hormonal therapy in transmen and reports that it is reasonably safe, suggesting monitoring should be frequent initially but can be less frequent over time.

This review discusses the potential impact of endocrine-disrupting chemicals and body size on pubertal onset and progression, highlighting critical gaps and priorities for future research without presenting new clinical results.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

This article discusses various causes of hyperandrogenism in women and highlights diagnostic considerations for conditions such as PCOS, NCCAH, Cushing's disease, and androgen-secreting tumors, without reporting new clinical results.

This article reviews existing knowledge on postmenopausal hyperandrogenism and highlights diagnostic challenges, reporting no new clinical results.

This review discusses the role of oestrogens in stimulating linear bone growth and pubertal changes in both boys and girls, highlighting their influence on the growth hormone-insulin-like growth factor axis; it reports no new clinical results.

This review discusses the regulation of hair growth, causes of excessive androgen secretion, and current safe solutions for hyperandrogenism manifestations in women but reports no new clinical results.

This study found that the gene SRD5A1, associated with methylation changes due to early-life environment, may play a role in altering reproductive phenotypes in women by delaying pubertal onset and decreasing ovarian reserve.

This study found that both declining levels of the neurosteroid THP and increasing levels of estradiol before puberty trigger maximal expression of α4βδ GABAA receptors in the CA1 hippocampus of female mice.

In this review, anabolic steroid use was reported to increase risks such as cardiovascular issues, liver damage, endocrine disruptions, and musculoskeletal injuries, with psychological impacts also noted, underscoring the need for education and preventive strategies.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

This study found evidence suggesting that hypertrichosis may be an adverse effect of inhaled corticosteroids in children, although it does not always resolve after stopping treatment.

This review covers the pathophysiology, diagnosis, and treatment of nonclassic congenital adrenal hyperplasia due to P450c21, but it reports no new clinical results.

In this study, Chinese children with central precocious puberty receiving 6-monthly injections of triptorelin showed luteinizing hormone suppression and slowed development of sexual characteristics over 12 months, without severe adverse events, suggesting it may be an effective treatment option for this population.

This review highlights therapeutic options for inducing puberty in males and females with delayed puberty, emphasizing the need for larger trials to establish the best approaches.

This review discusses diagnostic and management approaches for hirsutism, emphasizing that most cases are due to polycystic ovary syndrome or obesity-related disorders, with idiopathic hirsutism often treated cosmetically.

This review summarizes the clinical features and molecular causes of Primary Generalized Glucocorticoid Resistance, highlighting new findings from the characterization of mutations in the NR3C1 gene, but reports no new experimental results.

This review discusses the role of oestrogens in stimulating growth hormone secretion and influencing linear bone growth in children, and reports no new clinical results; the authors suggest that oestrogens play a key role in pubertal growth spurts for both genders.

This study found that canrenone significantly reduced hair growth and decreased certain androgen levels in women with idiopathic post-puberal hirsutism, suggesting potential effectiveness as a treatment.

This review discusses the pathophysiology, diagnosis, and management of functional hypothalamic amenorrhea in adolescent girls and reports no new clinical results.