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Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

Puberty involves complex hormonal changes, varies by gender and ethnicity, and requires careful monitoring for abnormalities.

Higher early lead exposure is linked to delayed puberty in girls.

Higher fluoride levels may delay puberty in boys.

PFAS exposure in adolescence may delay puberty in females.

Low selenium intake may delay puberty in boys but not in girls.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

Girls with PCOS often start puberty earlier and have signs of insulin resistance from a young age.

Recurrent vaginal bleeding in young girls without puberty signs may require a genital exam to find hidden causes.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Babies who gain weight quickly, especially in the first 3 months, may start puberty earlier.

A fungal infection can look like a different scalp condition in teens, leading to wrong treatment until proper tests are done.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.

Darker skin in 10-year-old girls may be an early sign of puberty.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Precocious puberty is starting earlier due to factors like obesity and chemicals, with treatment focusing on preserving height and addressing social issues.

Treating classic 21-hydroxylase deficiency requires precise glucocorticoid dosing and attention to individual patient needs, with new treatments showing promise.

The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.

Oestrogens are key for bone growth during puberty in both boys and girls.

A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

Excessive hair growth in women can be treated with medications like spironolactone and finasteride, and male-pattern baldness in women can be improved with similar treatments.

Some autistic children may have higher levels of male hormones, which could be linked to aggression.

A boy's early puberty caused by a testicular tumor returned to normal after surgery.

Testosterone affects stress hormone levels differently in adolescent and adult male rats.