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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

PCOS is a common condition in women that can lead to infertility and other health issues, and it's diagnosed by specific criteria with various treatment options available.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

A 23-year-old woman's missed periods were caused by a rare genetic disorder treated with hormone patches.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Darker skin in 10-year-old girls may be an early sign of puberty.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Homeopathic remedies can help manage PCOS symptoms in girls aged 17-21.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Diet, especially dairy and high-sugar foods, can cause acne.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Both estrogens and androgens are important for health in both males and females.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Prolactin and melatonin can stimulate hair growth in Cashmere goat hair follicles, but melatonin may reduce follicle viability over time.