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Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Higher early lead exposure is linked to delayed puberty in girls.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Gender-affirming care for youth remained essential during the COVID-19 pandemic, with telemedicine playing a key role.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

PFAS exposure in adolescence may delay puberty in females.

Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Testosterone affects stress hormone levels differently in adolescent and adult male rats.

Men who went through puberty later had lower sperm counts and altered hormone levels, possibly affecting fertility.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Some autistic children may have higher levels of male hormones, which could be linked to aggression.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.

Higher fluoride levels may delay puberty in boys.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Girls with PCOS and menstrual disorders have notably higher androgen hormone levels.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Low selenium intake may delay puberty in boys but not in girls.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.