42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
41 citations,
October 2008 in “The American journal of pathology” Blocking a specific protein signal can make hair grow on mouse nipples.
33 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
30 citations,
February 2018 in “Journal of Pharmacy and Pharmacology” Hedychium spicatum has medicinal properties but needs more research for scientific validation and use.
28 citations,
August 2000 in “Current Opinion in Chemical Biology” Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.
26 citations,
September 2018 in “Neurobiology of Disease” Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
26 citations,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
25 citations,
May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
20 citations,
September 2013 in “Anti-Cancer Drugs” PTH-CBD could help prevent and treat hair loss caused by chemotherapy in mice.
20 citations,
October 2008 in “Archives of dermatological research” Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
19 citations,
October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
16 citations,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
15 citations,
May 2019 in “PLOS ONE” Substances from dental stem cells might help treat hair loss.
15 citations,
July 2013 in “Cell Reports” Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.
14 citations,
October 2020 in “Journal of ethnopharmacology” Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
8 citations,
April 2014 in “Anti-Cancer Drugs” A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.
5 citations,
December 2005 in “Clinical Techniques in Equine Practice” Skin and hair changes in horses can indicate serious diseases, and recognizing these signs is important for treatment and management.
4 citations,
January 2011 in “Medical Hypotheses” 3 citations,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
3 citations,
January 2015 in “Nasza Dermatologia Online” Some treatments for autoimmune hair loss work, but JAK inhibitors like tofacitinib are promising for regrowth.
3 citations,
February 2005 in “Expert Opinion on Investigational Drugs” New treatments for hair loss are being developed using molecular biology.
2 citations,
December 2023 in “Journal of clinical immunology” Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.
2 citations,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.
2 citations,
March 2013 in “Phytotherapy Research” Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.
2 citations,
January 2012 in “InTech eBooks” Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.
1 citations,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Goat skin changes with the seasons due to genes affected by daylight and hormones.
1 citations,
March 2015 in “Journal of Visualized Experiments” Researchers developed a new, precise method to measure hair loss in mice using image analysis.
1 citations,
May 2006 in “Expert Opinion on Therapeutic Patents” No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.
1 citations,
July 1998 in “JAMA” The book provides a historical view of abortion in the U.S., critiques the pro-choice movement, and recommends including abortion in medical education.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.