research Development of an Intrinsic Skin Sensor for Blood Glucose Level with CRISPR-Mediated Genome Editing in Epidermal Stem Cells
Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.
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research Gene Expression Profiling of Human Keratinocytes Exposed to the Hair-Dyeing Agent, m-Aminophenol
m-Aminophenol in hair dye can cause skin cell toxicity and stress responses.
research PSS20 Mediation Modeling and Measurement Characteristics of the Itch Severity Score from a Phase 2B Trial of Oral CP-690-550 in Patients with Moderate-to-Severe Plaque Psoriasis
CP-690,550 significantly reduced itching in patients with moderate-to-severe plaque psoriasis.
research Real-Life Dosing of Biologics in Plaque Psoriasis—A German Survey
Real-life dosing of biologics for plaque psoriasis often deviates from recommended guidelines, especially for high-need patients.
research Registrars’ Symposium: Summaries of Papers
Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.
research Efficacy of Minoxidil Combined With Photobiomodulation for the Treatment of Male Androgenetic Alopecia: A Double-Blind Half-Head Controlled Trial
Minoxidil and photobiomodulation together improve hair growth better than minoxidil alone.
research Examination of Hair Growth Parameters in Androgenetic Alopecia in Women Using TrichoScan
TrichoScan is reliable for counting and measuring hair density but may not accurately assess hair types in women with hair loss.
research Androgenetic Alopecia: Role of the Phototrichogram
Phototrichogram helps assess hair loss severity.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
research The Physiological and Pharmacological Roles of Prostaglandins in Hair Growth
Targeting the PGD2-DP2 pathway may help treat hair loss.
research A Modified Sobel Filter-Based Automated Numerical Algorithm Enables Immediate Trichoscopic Assessment of Hair Diameter Diversity in Male and Female Pattern Hair Loss
A new computer tool quickly measures hair thickness differences in people with common types of hair loss.
research After Skin Wounding, Noncoding dsRNA Coordinates Prostaglandins and Wnts to Promote Regeneration
After skin is damaged, noncoding dsRNA helps prostaglandins and Wnts work together to repair tissue and promote hair growth.
research Exhaustive Analysis of Scalp Hair Regression: Subjective and Objective Perception from Initial Hair Loss to Severe Miniaturization and Drug-Induced Regrowth
Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.
research Real-World Effectiveness, Safety, and Tolerability of Cetosomal Minoxidil 5% Alone and in Combination With Finasteride 0.1% in the Management of Androgenetic Alopecia
Cetosomal minoxidil alone and with finasteride is effective and well-tolerated for hair loss treatment.
research Multicenter Prospective Study on the Efficacy of Narrowband Ultraviolet B Treatment and Its Effect on Quality of Life, Anxiety, Depression in Plaque Psoriasis Patients
Narrowband Ultraviolet B treatment can significantly reduce anxiety in psoriasis patients, but it doesn't significantly affect depression.
research Influence of Human Placenta Extracts on Prostanoids Production in Cultured Hair Follicle-Derived Keratinocytes: The Possibility of Pharmaceutical Regenerative Medicine
Human placenta extract may promote hair growth by affecting certain lipid compounds.
research The Impact of VDR Expression and Regulation In Vivo
VDR regulation varies by tissue and is crucial for its biological functions.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Neonatal Derived Mesenchymal Stem Cell Mesotherapy in Androgenetic Alopecia: A Retrospective Observational Study and Review of Literature
Neonatal mesenchymal stem cell therapy shows promise for treating hair loss but needs more research.
research The Proportion of Catagen and Telogen Hair Follicles in Occipital Scalp of Male Androgenetic Alopecia Patients: Challenging the Established Dogma
The belief about hair shedding phases is likely incorrect and needs reevaluation.
research Are Hair Cortisol Levels Dependent on Hair Growth Rate? A Pilot Study in Rhesus Macaques
Monkey hair cortisol levels are not affected by how fast their hair grows.
research Genomic Markers and Personalized Medicine in Androgenetic Alopecia: A Comprehensive Review
Personalized treatments for hair loss are becoming more effective by using genetic information.
research Utilizing SNP Association Analysis as a Prospective Approach for Personalizing Androgenetic Alopecia Treatment
Genetic factors could lead to personalized treatments for hair loss.
research Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men With Androgenetic Alopecia
Prostaglandin D2, found in higher levels in bald scalps, stops hair growth and could be a target for treating hair loss.
research An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin
The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Autotaxin–Lysophosphatidic Acid–LPA3 Signaling at the Embryo-Epithelial Boundary Controls Decidualization Pathways
LPA3 signaling in the uterus is crucial for placental formation and fetal development.
research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin
sPLA2-X is crucial for normal hair growth and follicle health.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research Lifestyle Factors Involved in the Pathogenesis of Alopecia Areata
Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.