research Androgenetic Alopecia: Combing the Hair Follicle Signaling Pathways for New Therapeutic Targets and More Effective Treatment Options
New treatments for hair loss may target specific pathways and generate new hair follicles.
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research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation
Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
research Transcriptomic Regulation of Seasonal Coat Color Change in Hares
Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
research Identification of Ultraviolet B Radiation-Induced MicroRNAs in Normal Human Dermal Papilla Cells
UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
research Synchronous Profiling and Analysis of mRNAs and ncRNAs in the Dermal Papilla Cells from Cashmere Goats
Non-coding RNAs help control hair growth in cashmere goats.
research Severe Diffuse Non-Scarring Hair Loss in Systemic Lupus Erythematosus: Clinical and Histopathological Analysis of Four Cases
Hair loss in systemic lupus erythematosus patients is unique and improves with treatment.
research No Improvement in Male-Pattern Hair Loss Using Laser Hair-Comb Therapy: A 6-Month, Half-Head, Assessor-Blinded Investigation in Two Men
Laser hair-comb therapy doesn't improve male-pattern hair loss.
research A Pilot Study of a Grape Seed Procyanidin Extract for Lung Cancer Chemoprevention
Grape seed extract may safely and effectively help prevent lung cancer.
research A Genomic Approach to Susceptibility and Pathogenesis Leads to Identifying Potential Novel Therapeutic Targets in Androgenetic Alopecia
Genomic approach finds new possible treatments for hair loss.
research Compilation of a Comprehensive Gene Panel for Systematic Assessment of Genes That Govern an Individual’s Drug Responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Comparative Transcriptome Profiling Provides New Insights Into Mechanisms of Androgenetic Alopecia Progression
AGA progression involves increased lipid synthesis, electron transport, and hair follicle miniaturization.
research Identification of MicroRNAs Involved in Growth Arrest and Cell Death in Hydrogen Peroxide-Treated Human Dermal Papilla Cells
Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.
research Androgenetic Alopecia and Polymorphism of the Androgen Receptor Gene (SNP rs6152) in Patients with Benign Prostate Hyperplasia or Prostate Cancer
Hair loss gene linked to prostate issues.
research Gene Expression Profiling of the Intact Dermal Sheath Cup of Human Hair Follicles
Researchers found specific genes in the part of hair follicles that could help treat hair disorders.
research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research 15-Deoxy Prostaglandin J2, The Nonenzymatic Metabolite Of Prostaglandin D2, Induces Apoptosis In Keratinocytes Of Human Hair Follicles: A Possible Explanation For Prostaglandin D2-Mediated Inhibition Of Hair Growth
A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.
research Proteomic Analysis of Balding and Non-Balding Mesenchyme-Derived Dermal Papilla Cells from Androgenetic Alopecia Patients Using Online Two-Dimensional Reversed Phase-Reversed Phase LC-MS/MS
Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
research Can Plant-Derived Phytochemicals Provide Symptom Relief for Hair Loss? A Critical Review
Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
research Single-Cell Profiling Reveals a Potent Role of Quercetin in Promoting Hair Regeneration
Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.
research Blood MUC-18/MCAM Expression in Patients with Melanoma: A Suitable Marker of Poor Outcome
High MUC-18/MCAM levels in blood indicate a worse outlook for melanoma patients.
research Qualification of a New and Precise Automatic Tool for the Assessment of Hair Diameters in Phototrichograms
The new automatic tool accurately measures hair thickness and is reliable.
research Genetic Analysis of a Novel Antioxidant Multi-Target Iron Chelator, M30, Protecting Against Chemotherapy-Induced Alopecia in Mice
M30 is a promising treatment for preventing hair loss during chemotherapy.
research Investigating the Safety and Efficacy of Platelet-Rich Plasma Treatment for Female Androgenetic Alopecia: Review of the Literature
PRP treatment may promote hair growth and improve hair density in women with AGA, but more research is needed.
research Transcriptomic Profiling in Silurana Tropicalis Testes Exposed to Finasteride
Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
research Tp63-Expressing Adult Epithelial Stem Cells Cross Lineage Boundaries Revealing Latent Hairy Skin Competence
Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
research Nuclear Factor (Erythroid-Derived 2)-Like-2 Pathway Modulates Substance P–Induced Human Mast Cell Activation and Degranulation in the Hair Follicle
Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
research Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles
AGA linked to inflammation, stress, fibrosis, and disturbed hair follicle stem cells.
research Standard DNA Methylation Analysis in Mouse Epidermis: Bisulfite Sequencing, Methylation-Specific PCR, and 5-Methyl-Cytosine Immunological Detection
These methods help understand DNA changes in mouse skin.
research Characterization of a Mouse Scube3 Reporter Line
Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
research Thy1 Marks a Distinct Population of Slow-Cycling Stem Cells in the Mouse Epidermis
A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.