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Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Understanding where cancer cells come from helps create better prevention and treatment methods.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Targeted cancer therapies often cause serious skin problems that need careful management.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Applying a special compound can promote hair growth without harmful side effects.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.