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Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.

New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

Hedgehog signaling controls hair follicle development and can affect skin cancer growth.

LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.

Boswellia may improve skin inflammation symptoms and positively influence hair growth in mice.

New hair regrowth model proposed, imiquimod found to kill skin cancer cells, T-cadherin loss linked to invasive skin cancer, no clear gene link to skin cancer after transplant, and study on children's hair loss shows male dominance and genetic ties.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

Sulforaphane from broccoli can help protect skin from sun damage.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.

Laser hair-comb therapy doesn't improve male-pattern hair loss.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Putting thymidine dinucleotide on newborn mice's skin can delay and reduce skin cancer.

The research suggests new treatments for skin cancer could target specific cell growth pathways.

CD4+ skin cells may be precursors to basal cell carcinoma.

The treatment was ineffective in humans.