Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that midazolam improved PTSD-associated behavioral deficits in rats through its action on the TSPO, CBR, and neurosteroidogenesis pathways.

This study found that rosemary oil from PT. Eteris Nusantara meets European Pharmacopoeia quality standards and is suitable for further hair growth pharmaceutical formulation.

This study found that the anticonvulsant effects of progesterone against PTZ-induced seizures in mice require conversion to allopregnanolone, as shown by the reversal of these effects with a 5alpha-reductase inhibitor.

This study found that a genetic variation in SRD5A2 influences the severity of PTSD symptoms in a sex-specific manner among traumatized African-American males.

This study indicates that approximately 18% of discharged COVID-19 patients experience PTSD, highlighting the need for attention to their long-term mental health.

In vitro, this study found that PTX and HU SF-FA NLCs showed greater cytotoxicity and apoptosis in ovarian cancer cells than pure paclitaxel, suggesting promise as a targeted drug delivery platform.

This study found that Epiprofin acts as a negative regulator of parathyroid hormone transcription, with potential implications for controlling PTH production in hyperparathyroidism.

This article presents a discussion amongst surgeons on treatment approaches for a male patient with severe pseudoptosis of the upper eyelid and brow ptosis, but reports no clinical outcomes.

This study found high levels of anxiety, depression, and PTSD in dermatology patients one year after the February 6, 2023, earthquakes in Türkiye, with specific skin conditions like telogen effluvium and alopecia areata being more prevalent among those with psychological distress.

This study found that minimally invasive combined fascia sheath suspension improved eyelid symmetry in patients with unilateral ptosis, particularly in measures of marginal reflex distance and eyelid contour.

This review found that patients with depression generally have higher hair cortisol concentrations compared to healthy controls, while those with PTSD tend to have lower concentrations.

This study found that letrozole, an aromatase inhibitor, reduced the incidence and severity of PTZ-induced kindling seizures in mice, potentially due to its effects on 17β-estradiol and neurosteroid synthesis.

In this study, researchers found that both direct and witnessed trauma in mice are associated with reduced levels of the neurosteroid allopregnanolone, potentially influencing PTSD outcomes, and that treatment with synthetic neurosteroids may mitigate fear responses linked to observed trauma.

Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.

In this study, researchers found that both direct and witnessed trauma in mice were linked to lower levels of the neurosteroid allopregnanolone, and that boosting neurosteroidogenesis may alleviate PTSD-like symptoms, suggesting potential treatment strategies for PTSD stemming from either trauma type.

This study reports that a brow-suspension suture procedure safely and effectively restored normal brow levels with minimal recovery time for all nine patients with brow ptosis.

New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.

This review discusses the mechanisms of platinum-induced peripheral neuropathy related to reactive oxygen species and explores potential antioxidant therapies and nanotechnology approaches, but reports no new clinical results.

This case study detailed a rare instance of Penile Thread Tourniquet Syndrome in a 10-year-old boy, where a thread caused localized infection and edema without urethral damage, ultimately resulting in a favorable outcome through surgical and conservative management.

This report describes an unusual case of proliferating trichilemmal cyst with trichoepitheliomatous change in a young woman, differing from its typical presentation in elderly women.

This review describes how curcumin, a compound derived from turmeric, affects various cell signaling pathways involved in cancer progression, highlighting its potential as a therapeutic agent with fewer side effects compared to conventional cancer treatments.

This study suggests that ovarian cycle-related progesterone and neurosteroids regulate α2-subunit expression of GABA-A receptors in the hippocampus through a pathway independent of progesterone receptors, potentially affecting brain conditions linked to the menstrual cycle.

This study found that enhanced neurosteroid synthesis likely mediated by the translocator protein contributed to the anticonvulsant action of midazolam in mice.

This case study reports a near-complete response of a proliferating trichilemmal tumor to neoadjuvant radiotherapy in a 79-year-old woman, highlighting radiotherapy's role in managing this condition when patients are unsuitable for surgery.

This study concluded that CNS1-dependent peripheral Tregs do not significantly impact type 1 diabetes in the NOD mouse model, with thymus-derived Tregs being the primary regulators.

This study developed and tested a new injectable hydrogel for chronic diabetic wounds, reporting significant improvements in wound healing through enhanced angiogenesis, epithelization, and reduction of inflammation and infection in animal models.

This retrospective study found that a majority of patients with low vitamin D levels also exhibited secondary hyperparathyroidism, highlighting the relationship between vitamin D deficiency and increased parathyroid hormone levels.

This study found that METTL1 is upregulated in papillary thyroid cancer tissues and promotes cancer cell proliferation and metastasis through its tRNA methyltransferase activity.

This case report describes a patient experiencing nail nonadherence due to sterile matrix scarring associated with valproic acid use, and suggests nail bed excision with sterile matrix grafting as a potential surgical solution.

This case report describes the first successful use of telitacicept in treating a patient with systemic lupus erythematosus and a history of papillary thyroid carcinoma, suggesting its potential as a therapeutic option for such conditions.