54 citations
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January 2013 in “BMC Complementary and Alternative Medicine” In this study, topical application of Thuja orientalis extract promoted hair growth by inducing the anagen phase and increasing hair follicle size and number in telogenic mice.
14 citations
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January 2015 in “Clinical Nutrition Research” This clinical trial found that the extract complex of Cistanche tubulosa and Laminaria japonica (MK-R7) significantly improved hair density and diameter in patients with patterned hair loss over 16 weeks.
13 citations
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May 2019 in “Cancer Prevention Research” This study found that a three-month regimen of leucoselect phytosome, a grape seed extract complex, was well tolerated and significantly reduced bronchial proliferation markers in heavy active and former smokers.
2 citations
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January 2025 in “Pharmaceutical Research” This article reviews the possible therapeutic activities of Angelica gigas Nakai root extracts and their components, noting their potential effects on neuro-cognitive, metabolic, and other health conditions, and reports no new clinical results.
May 2024 in “International journal of nanomedicine” This review highlights the potential of extracellular vesicles derived from medicinal plants as therapeutics for diseases such as cancer and inflammation, suggesting they may enhance the clinical use of herbal preparations, despite the challenges posed by extract complexity and individual variability.
January 2006 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study found that Rubus coreanum extract promotes hair growth in mice, but its effects are not due to inhibition of specific enzymatic activities or growth factor expression.
1 citations
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October 2024 in “Journal of King Saud University - Science” In this in vitro study, extracts from Tridax procumbens demonstrated potential antioxidant and anticancer activity against various human cancer cell lines, with notable efficacy in specific fractions.
12 citations
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April 2023 in “Nano Biomedicine and Engineering” This study synthesized silver nanoparticles using an Artocarpus heterophyllus leaf extract and found that these nanoparticles, with a size of 100–110 nm, displayed effective antioxidant, antibacterial, and antifungal activities in vitro.
4 citations
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September 2024 in “Jurnal Pengolahan Hasil Perikanan Indonesia” In this study, researchers reported that compounds from Bruguiera gymnorhiza leaves showed anti-inflammatory potential in in silico analyses, with favorable drug properties and specific binding to the IKKβ receptor, suggesting possible development into anti-inflammatory drugs.
9 citations
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August 2005 in “Experimental Dermatology” In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.
March 2026 in “Folia Histochemica et Cytobiologica” This review highlights LTBP1 as a critical integrator in disease processes, showing its dual role in cancer progression and suppression, its pathological influence in fibrosis, and its contribution to various disorders, suggesting its potential as a biomarker and therapeutic target.
July 2025 in “Scientific Reports” In this study, researchers identified six novel prognostic biomarkers for bladder cancer and developed a predictive model that effectively stratifies patients into high-risk and low-risk groups based on immune cell infiltration differences and gene expression.
September 2025 in “International Journal of Environmental Sciences” This study explored the stem of Moullava spicata and found it to be rich in secondary metabolites and natural antioxidants, showing significant concentration-dependent antioxidant activity, which supports its ethnomedicinal use and provides a basis for further pharmacological research.
2 citations
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January 2022 in “Journal of Oleo Science” This study found that oil from CG17 garden cress seeds had higher amounts of β-carotenoids, tocopherols, and vitamins compared to other genotypes, with varying physiochemical properties across all seeds.
August 2024 in “Majalah Obat Tradisional” This study found that microemulsions containing ethanol extract of cayenne pepper were effective in enhancing hair growth in rabbits, with the 0.2% concentration achieving the most significant results over a 30-day period, compared to a negative control.
July 2012 in “Ubaya Repository (University of Surabaya)” This study found that hair growth gel and tonic containing red grape seed extract were physically and chemically unstable under high temperature and humidity conditions over 30 days.
4 citations
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November 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study found that a hydro-alcoholic extract of Roselle petals may reduce free radical production during UV-induced photodecomposition of antibiotics, potentially offering protective benefits for patients using similar topical antibiotics.
1 citations
,
May 2023 in “International Journal of Applied Pharmaceutics” In this study, the researchers developed a novasome vesicle carrying bovine placenta extract, which demonstrated superior hair growth effects in rats compared to traditional minoxidil and PE-loaded liposomes, and showed good stability and physical characteristics over 90 days at 4°C.
January 2026 in “JURNAL PIJAR MIPA” This study found that ethanol extracts from Marygold flowers significantly promote hair growth in male rabbits, with the highest concentration (20%) leading to longer and denser hair compared to lower concentrations.
This study found that an ethanolic extract of Ganoderma lucidum, especially at 15mg/kg, may promote hair growth in a rat model of testosterone-induced alopecia, showing effects comparable to minoxidil.
November 2014 in “PubMed” This article discusses the potential of a robotic surgical device to overcome limitations of traditional hair restoration methods, but reports no new clinical results and calls for further testing.
320 citations
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December 2018 in “Frontiers in Immunology” This review explores how preconditioning mesenchymal stromal cells can impact their secretome's therapeutic potential in regenerative medicine, emphasizing immunomodulatory and regenerative functions, but provides no new clinical results.
26 citations
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March 2020 in “Antioxidants” This study found that microwave-assisted Opuntia humifusa extract improved antioxidant and anti-inflammatory properties to counteract particulate matter's harmful effects on HaCaT keratinocytes.
11 citations
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August 2024 in “Nature Communications” In this study, researchers observed that quiescent mouse embryonic fibroblasts showed reduced glycolysis but increased TCA cycle flux and mitochondrial respiration, with these changes linked to metabolic reprogramming involving yes-associated protein inhibition and malate cycle modulation, which supports extracellular matrix protein synthesis.
8 citations
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May 2021 in “Bioengineering & translational medicine” This review examines the challenges of hair follicle regeneration and outlines strategies for bioengineering human hair follicle models, without presenting new experimental results.
147 citations
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November 2020 in “International Journal of Molecular Sciences” This review discusses the immune roles of keratinocytes in wound healing and chronic wound inflammation, emphasizing their potential impact on chronic wound pathology and highlighting areas for future research.
31 citations
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February 2019 in “International Journal of Cosmetic Science” This study found that ultraviolet radiation negatively affects hair follicle functions in human scalp skin, and caffeine application may provide some protective effects against this damage.
18 citations
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April 2010 in “Actas Dermo-Sifiliográficas” This review discusses the current procedure for follicular unit hair transplantation, emphasizing its natural and reproducible results, but does not report new clinical findings.
17 citations
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November 2017 in “Dermatologic Clinics” This article discusses advancements in hair restoration, highlighting the use of robotics and follicular unit extraction along with adjuvant therapies like platelet-rich plasma, but presents no new clinical findings.