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The document concludes that diagnosing and managing plaque psoriasis, particularly in sensitive areas, is challenging and requires careful differentiation from similar skin conditions.

The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.

Psoriasis patients have more comorbidities, including autoimmune diseases and other health issues, than those without psoriasis.

High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.

Mitochondrial dysfunction links metabolic syndrome and inflammatory skin diseases, suggesting targeted therapies and lifestyle changes.

New technologies help us better understand how skin microbes affect skin diseases.

Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.

Stump-tailed macaque best for researching hair loss causes and treatments.

Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.

TRα and CRABPII genes change their activity levels during goat fetal skin development.

IL-36α helps grow new hair follicles and speeds up wound healing.

3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.

Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.

Near-infrared LED light improves skin rejuvenation and hair growth better than white LED light.

Inhibiting PLA2 enzymes may help treat inflammatory skin diseases like psoriasis and dermatitis.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.

Hairless HRS/J mice resist Bacillus anthracis skin infections due to high numbers of immune cells, not because they lack hair follicles.

The 532 nm laser effectively reduces facial vascular and pigmented lesions, with the VISIA system reliably assessing treatment results.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Human skin has less GDNF and its receptor with age.

Psoriasis is linked to a higher risk of autoimmune diseases and other health conditions.

Not having enough cystatin M/E protein causes less hair growth and dry skin.

People with psoriasis have more health problems, including autoimmune diseases, than those without it.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.