July 2018 in “Our Dermatology Online” Alopecia areata does not affect areas with psoriasis plaques.
March 2017 in “Trichology and cosmetology:” Psoriasis treatment may affect body hair growth, with a complex relationship between skin and hair growth mechanisms.
Psoriasis is a genetically influenced, immune-mediated inflammatory skin disease affecting over 60 million people globally, with chronic plaque psoriasis being the most common form. Genetic loci like PSORS1 and CARD14 are significant, and environmental factors such as infections, stress, and lifestyle choices impact disease onset and severity. Stress-reducing interventions can enhance treatment efficacy. The Koebner phenomenon and the roles of innate and adaptive immunity are crucial in its pathogenesis. Psoriasis plaques involve a complex inflammatory network, and targeted biologic treatments show promise. While scalp psoriasis typically does not cause hair loss, severe forms like erythrodermic psoriasis can. The disease can present in infancy and affect genital skin in inverse psoriasis.
18 citations,
April 2010 in “Archives of Dermatology” Psoriasis or contact dermatitis can override alopecia areata, allowing hair growth.
Men with both baldness and scalp psoriasis often don't have psoriasis on bald spots.
104 citations,
September 2008 in “Clinics in Dermatology” Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.
45 citations,
January 2010 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
25 citations,
September 2013 in “Actas Dermo-Sifiliográficas” Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.
24 citations,
January 2017 in “Acta dermato-venereologica” Tofacitinib helped a young woman's severe hair loss and arthritis but not her plaque psoriasis.
4 citations,
November 2020 in “Psoriasis : Targets and Therapy” The document concludes that proper treatment and management of plaque psoriasis in adolescents can improve their quality of life.
1 citations,
November 2018 in “Dermatologic Therapy” Compounded topical preparations should be used with caution for severe psoriasis and generally come after systemic treatments.
1 citations,
April 2024 in “Skin research and technology” Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
15 citations,
June 2015 in “F1000Research” Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.
January 2019 in “Elsevier eBooks” Up to half of people experience itchy scalp, often due to skin conditions like seborrheic dermatitis or psoriasis, and treatments vary based on the specific cause.
31 citations,
September 2014 in “International Journal of Dermatology” Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.
September 2011 in “Journal der Deutschen Dermatologischen Gesellschaft” Effective treatments for scalp psoriasis include glucocorticosteroids, Vitamin D3 analogs, and combination therapies like calcipotriol and betamethasone dipropionate.
176 citations,
November 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
60 citations,
May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
32 citations,
August 2020 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
1 citations,
February 2004 Skin diseases are common and can significantly affect people's lives; better outcome measures and ethical clinical trials are needed to improve dermatology care.
77 citations,
June 2017 in “Advances in Therapy” New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.
14 citations,
May 2014 in “Medical Clinics of North America” The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.
23 citations,
December 2021 in “Frontiers in Immunology” IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
5 citations,
May 2022 in “Molecules” Botulinum toxin is effective for various skin conditions, but more research and awareness of side effects are needed.
140 citations,
April 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Liposomes improve drug delivery and reduce skin irritation in dermatology.
64 citations,
October 2019 in “Materials Science and Engineering: C” Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.
51 citations,
October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
7 citations,
March 2006 in “Clinical and Experimental Dermatology” Using anabolic steroids 'Sus' and 'Deca' for bodybuilding caused severe acne in a man.
The document concludes that dermatology training and grading scales need to better represent dark-skinned individuals to improve diagnosis and assessment of skin conditions.
29 citations,
March 1983 in “Journal of The American Academy of Dermatology” New treatments for psoriasis have improved effectiveness and may reduce long-term side effects when combined with standard therapies.