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Topical calcineurin inhibitors, especially 0.1% tacrolimus ointment, are effective and well-tolerated for treating cutaneous lupus erythematosus but require more research for standard treatment guidelines.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.

A 15-year-old boy's severe scalp condition improved significantly with adalimumab and baricitinib treatment.

The Polish Dermatological Society recommends personalized treatment for cutaneous lupus, including lifestyle changes, medications, and monitoring, with specific drugs for severe cases.

Consider necrolytic acral erythema in similar cases and treat with oral zinc sulfate.

A young man's hair loss was the only sign of syphilis, which improved after treatment.

Nearly half of children with primary immunodeficiency disorders showed skin problems, often as the first sign of their condition.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Some psychoactive drugs can cause skin reactions, with carbamazepine having a higher risk, and stopping the drug and seeing a dermatologist is important.

HIV can cause skin disorders, which are often the first sign of infection, especially in people with darker skin.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

TNF-alpha inhibitors can cause various immune-related skin issues.

The document concludes that skin and nail changes can indicate various underlying health conditions.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

The skin microbiome helps heal wounds and can be targeted to improve healing.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Psychotropic medications can cause skin problems but also treat some skin conditions.

ceRNA networks offer potential treatments for skin aging and wound healing.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

β-blockers can cause skin problems like psoriasis and vitiligo, and doctors should tell patients about these risks.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The document describes skin diseases affecting the outer ear in dogs and cats, their spread to other body parts, and treatment options.

Skin reactions to antidepressants are common but usually not serious and can be treated.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Skin problems are very common in people with end-stage kidney disease.

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

Mood stabilizers can cause serious skin reactions; careful monitoring and immediate treatment are crucial.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.