27 citations
,
February 2021 in “Clinical and Experimental Dermatology” This review synthesizes recent studies and suggests that Curcuma species may provide various dermatological benefits, but further research is needed to determine optimal delivery methods and dosages.
27 citations
,
August 2016 This article discusses the importance of understanding the skin's structure and function for comprehending both healthy skin biology and skin disease pathophysiology, but reports no new findings.
27 citations
,
July 2015 in “International Journal of Dermatology” This study found that skin disorders are prevalent among elderly individuals and are often associated with underlying systemic diseases.
27 citations
,
January 2011 in “Dermatology Research and Practice” This review discusses the autoimmune pathogenesis of non-segmental vitiligo and highlights the genetic susceptibility linking it to other autoimmune disorders, but reports no new clinical results.
26 citations
,
October 2017 in “Clinical Reviews in Allergy & Immunology” This review explores skin manifestations associated with autoimmune liver diseases and highlights known and probable links, such as vitiligo's strong association with autoimmune hepatitis.
26 citations
,
January 2017 in “Acta dermato-venereologica” This review examines the use of monoaminergic antidepressants for inflammatory skin disorders and reports they may reduce dermatological symptoms, suggesting a potential role beyond treating psychiatric conditions.
26 citations
,
June 2024 in “Frontiers in Immunology” The authors discussed that SOCS1 and SOCS3's inhibition of JAKs plays a significant role in the development of JAK inhibitor drugs for skin inflammatory diseases and malignancies.
26 citations
,
October 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the potential benefits and biological activities of MSC secretome for various skin applications, but it reports no new clinical results.
26 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” This review discusses mesenchymal stromal cell-conditioned medium for various skin conditions and found improvements in wound healing, hair restoration, and more, but emphasizes the need for further research to validate these findings.
26 citations
,
May 2014 in “BioEssays” This review discusses how neuroendocrine pathways influence keratin regulation in human skin and hair follicles and suggests these pathways as potential targets for new treatments of skin disorders, but reports no clinical results.
26 citations
,
June 2012 in “The Journal of Obstetrics and Gynecology of India” This review discusses various skin changes during pregnancy, noting that while most are benign and resolve after childbirth, some may require careful medical management for the safety of the mother and fetus; it reports no new results.
25 citations
,
December 2015 in “Journal of the European Academy of Dermatology and Venereology” This study found that alopecia areata negatively affects patients' quality of life, though less severely than psoriasis, atopic dermatitis, and onychomycosis.
25 citations
,
January 2024 in “Journal of Lipids” This review reports that cubosomes, used as drug nanocarriers in topical treatments, offer potential benefits for managing skin and eye diseases by improving bioadhesion, retention, and sustained release compared to conventional formulations, but also face manufacturing and biological challenges for effective clinical outcomes.
25 citations
,
June 2022 in “Clinical and Experimental Dermatology” This review discusses how menopause affects skin structure and function, finding associations between menopause and common skin conditions, but reports no new clinical results.
25 citations
,
November 2021 in “Toxins” This review discusses the use of bee venom in skin cosmetics and highlights safety concerns related to potential immune reactions, but it reports no new clinical results.
25 citations
,
December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This study suggests that targeting specific immune pathways, such as IL-12/23 and Th2 cytokines, may offer new treatment options for alopecia areata, a T-cell-mediated disease without current mechanism-specific therapies.
25 citations
,
November 2015 in “Journal of Dermatological Science” In this study, researchers identified the antimicrobial peptide dermcidin in sebocyte lipid droplets, challenging the previous understanding of dermcidin as exclusively sweat-specific.
25 citations
,
July 2014 in “Hong Kong medical journal” This review discusses potential associations between Helicobacter pylori infection and various skin diseases but reports no new clinical findings; more research is needed to clarify these links.
25 citations
,
March 2012 in “Journal of Dermatological Science” This review discusses genome-wide association studies in dermatology, noting that variants linked to risk for 10 skin complex diseases have been identified, with potential implications for diagnostics and management; it reports no new clinical results.
25 citations
,
January 1983 in “Archives of dermatology” This article reviews the early establishment of dermatology as a specialty in the U.S. and documents the initial descriptive errors in understanding Darier's disease, offering no new clinical data.
25 citations
,
January 1978 in “JAMA” This case report describes a 45-year-old woman who developed Cushing's syndrome and hirsutism after using topically applied desoximetasone (Topicorte).
24 citations
,
July 2021 in “Pharmaceutics” This article reviews the JAK signaling pathway and the development of ruxolitinib cream as a targeted treatment for inflammatory skin diseases, reporting no new clinical results.
24 citations
,
March 2018 in “Experimental Dermatology” This review explores the role of regulatory T cells in autoimmune skin disorders like alopecia areata and vitiligo, emphasizing unanswered questions and reporting no new experimental results.
24 citations
,
March 2015 in “Dermatologic Surgery” This review discusses the modest efficacy of home-use laser and light devices for conditions like hair removal and acne, noting limited evidence and a lack of robust trials.
24 citations
,
September 2011 in “Autoimmunity” This review discusses the role of natural killer cells in the pathogenesis of blistering diseases and proposes further research on their interaction with the skin, reporting no new clinical results.
24 citations
,
March 2001 in “PubMed” In this study, the researchers reported a high prevalence of specific cutaneous lesions in the Freixo de Espada à Cinta population, with significant associations between demographic factors and lesion types.
23 citations
,
December 2021 in “Frontiers in Immunology” This review discusses the significance of IL-1 family cytokines in skin inflammation and pathology, emphasizing their interactions with microbes and potential therapeutic applications, but reports no new clinical results.
23 citations
,
September 2021 in “Clinical Cosmetic and Investigational Dermatology” This review discusses the dermatological applications of botulinum toxin, including off-label uses for various skin conditions, and calls for a better understanding of underlying muscular anatomy for effective clinical practice.
23 citations
,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” This article reviews the roles of lesser-known secreted phospholipase A2 isoforms in various biological processes, such as immune suppression, metabolic regulation, epidermal hyperplasia, and male reproduction, without reporting new clinical findings.
23 citations
,
April 1996 in “PubMed” This article reviews the role and clinical applications of 1,25-dihydroxyvitamin D3 and parathyroid hormone-related peptide in dermatology, with a focus on psoriasis treatment, and reports no new experimental findings.