8 citations
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July 2001 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This review summarizes the historical and evolving treatments for vitiligo, highlighting that combining medical and surgical approaches may enhance repigmentation outcomes, though more research and new protocols are needed.
This source reviews various alternative therapies for vitiligo, such as khellin, 5-fluorouracil, Ginkgo biloba, and more, noting that further research is needed to confirm their effectiveness and safety.
532 citations
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August 2011 in “Journal of the American Academy of Dermatology” This article discusses the clinical presentation, histopathologic findings, and pathogenesis hypotheses of vitiligo without reporting new clinical results.
281 citations
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January 2013 in “British Journal of Dermatology” Manage vitiligo with treatments, address emotions, and use camouflage techniques.
84 citations
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April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
67 citations
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August 2013 in “International Journal of Cosmetic Science” This review discusses the role of oxidative stress in hair greying and suggests that understanding melanocyte susceptibility at different follicular locations may help develop therapies for preventing and reversing the process; it reports no new experimental results.
19 citations
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July 2007 in “Dermatologic clinics” This paper discusses the need for a standardized classification and meta-analysis of treatments for hypopigmented disorders and reports no new clinical results.
11 citations
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January 2017 in “Oxidative medicine and cellular longevity” This study found that antroquinonol inhibited CD8+ T cell proliferation and reduced proinflammatory cytokine secretion in vitro, while also ameliorating H2O2-induced depigmentation and resisting reductions in hair follicle length, skin thickness, and tyrosinase expression in mice.
This chapter reviews recent developments in vitiligo research, highlighting the role of melanocyte stem cell differentiation and oxidative stress in its management, but reports no new clinical results.
2 citations
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January 2017 in “Journal of Pigmentary Disorders” This article discusses vitiligo, reviewing its symptoms, possible causes, and classification, but reports no new clinical findings.
1 citations
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January 2014 in “Elsevier eBooks” This review discusses melanocytes' role in pigmentation, their clinical significance in conditions like vitiligo and hair graying, and highlights current research on hair follicle regeneration without reporting new clinical results.
March 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study describes vitiligo as an autoimmune disease marked by depigmented skin and mucosal patches, and reviews its complex pathogenesis and diagnostic features. Treatment aims for disease control and repigmentation through various topical and systemic therapies, phototherapy, and surgical options, emphasizing personalized, multimodal approaches.
In this study involving 13 patients with vitiligo-associated leukotrichia, minimal hair repigmentation was observed following treatment with fractional CO₂ laser and topical betamethasone, though the method was well tolerated, highlighting the need for further research to optimize treatment parameters.
August 2024 in “Bioscience of Microbiota Food and Health” In this review, researchers examined the link between microorganisms and vitiligo, highlighting how microbes might impact the disease's development and suggesting avenues for better treatment strategies based on these interactions.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
November 2013 in “John Wiley & Sons, Ltd eBooks” This chapter reviews various mucocutaneous manifestations of endocrine disorders and provides illustrative images of these clinical features, but reports no new research findings.
May 2004 in “Pediatric Dermatology” Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.
August 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This article introduces a hypothesis linking the enzyme catalase in processed meats to higher cancer incidence due to its electromagnetic field emissions, but reports no new clinical results.
3 citations
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March 2014 in “Journal of Industrial Microbiology & Biotechnology” This study identified a cytochrome P450 enzyme, CYP-pa1 from Pseudonocardia autotrophica, as responsible for the specific hydroxylation of cyclosporin A at the 9th N-methyl leucine, suggesting potential for biotechnological applications.
4 citations
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August 2018 in “International Journal of Research -GRANTHAALAYAH” This article introduces a hypothesis that the enzyme catalase in processed meats may be a probable cause of higher cancer incidence due to its emission of electromagnetic fields, but no new clinical results are provided.
April 2022 in “Book Publisher International (a part of SCIENCEDOMAIN International)” This manuscript proposes a hypothesis that the enzyme catalase added to processed meats may emit electromagnetic fields and contribute to cancer development.
1 citations
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January 1992 in “DNA sequence” This study found that a cuticle keratin gene in sheep is a pseudogene due to gene duplication and mutations, lacking expression in vivo.
13 citations
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January 2013 in “Applied and Environmental Microbiology” This study found that regio-specific hydroxylation of cyclosporine A in Sebekia benihana is mediated by the cytochrome P450 hydroxylase CYP-sb21, suggesting potential biotechnological applications for hair growth promotion without immunosuppressive effects.
14 citations
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August 2014 in “The FASEB Journal” This study found that the catalytically inactive serine protease CAP1/Prss8 can still induce skin disorders in mice and is subject to inhibition by nexin-1, independent of its catalytic activity.
34 citations
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April 2012 in “Molecular Biology Reports” This study isolated a thermophilic bacterial strain, Bacillus cereus, from soil that produces an extracellular protease; the enzyme effectively removed non-leather structures from animal pelts and was compatible with commercial detergents.
May 2010 in “Europe PMC (PubMed Central)” This chapter discusses the synthesis and analysis of near-infrared fluorescent activity-based probes for imaging cysteine protease activity, reporting potential benefits for disease diagnosis but noting challenges in imaging specific locations with high cathepsin activity.
56 citations
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October 2007 in “Journal of Biological Chemistry” This study concluded that dilated cardiomyopathy in Ctsl-deficient mice is mainly due to the lack of cathepsin L in cardiomyocytes, with additional heart stress from the fur defect.
29 citations
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December 2017 in “Molecular therapy” This study found that enzyme replacement therapy in mice with a severe form of classical homocystinuria improved metabolic patterns and alleviated many clinical symptoms.
2 citations
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January 2023 in “Bioresource Technology Reports” This study suggests that using glycosidases to lyse the polysaccharides of Botryoccocus braunii may allow for the semi-continuous recovery of hydrocarbons while keeping the cells viable.
22 citations
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November 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that cathepsin L and transglutaminase 3 colocalize in the human hair bulb and nail matrix, suggesting their involvement in terminal differentiation within these epidermal appendages.