research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
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research Hierarchically Assembled Nanofiber Scaffolds With Dual Growth Factor Gradients Promote Skin Wound Healing Through Rapid Cell Recruitment
The new scaffold with two growth factors speeds up skin healing and reduces scarring.
research C19 and C21 5β/5α Metabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
research 5α-Reductase Isozymes and Androgen Actions in the Prostate
5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
research Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia
5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
research The Hair Cycle And Its Regulation
Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.
research Cloning, Expression, and Characterization of Rhesus Macaque Types 1 and 2 5alpha-Reductase: Evidence for Mechanism-Based Inhibition by Finasteride
Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Hair Transplantation, Scalp Reduction, and Flap Rotation in Black Men
Hair loss surgeries like grafts, scalp reductions, and flap rotations can be effective for black men with proper technique adjustments.
research Alopecia
The document concludes that correct diagnosis of alopecia types is crucial, scalp biopsies are important, and more research is needed.
research P-50 We Know You Are There: Missing Mass
Metyrapone can effectively treat Cushing's Disease even if the mass causing it is not found.
research Alcohol and Prostate Cancer: Time to Draw Conclusions
Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.
research Willingness to Pay for Hair Restoration Among Balding Men
Balding men value hair restoration highly, willing to pay over $5,000 for a slight improvement.
research Inhibition of Rat Alpha-Reductases by Finasteride: Evidence for Isozyme Differences in the Mechanism of Inhibition
Finasteride effectively blocks rat enzymes, but with varying methods and strength.
research Trichoscopic Findings of Frontal Fibrosing Alopecia
Trichoscopy is useful for diagnosing Frontal Fibrosing Alopecia.
research The Endoscopic Brow Lift
The document concludes that the endoscopic brow lift is a less invasive cosmetic surgery that requires careful technique and patient selection to achieve lasting, aesthetically pleasing results.
research Osler’s Phenomenon: Misdiagnosing Cushing’s Syndrome
Doctors often diagnose Cushing's syndrome late, which worsens symptoms; earlier detection is needed.
research Polycystic Ovary Syndrome: Overview and Management
PCOS is a common hormonal disorder in women, treated with lifestyle changes, medication, and patient education.
research Alopecia: A Pathologist's View
The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.
research Growth Hormone-Responsive Alopecia in Dogs
The exact cause of growth hormone-responsive alopecia in dogs is unclear.
research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder
Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
research Interventions for Alopecia Areata
Current treatments for alopecia show no significant long-term benefits.
research Adverse Cutaneous Reactions to Soft Tissue Fillers: A Review of the Histological Features
Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.
research Genome-Wide Association Study in Japanese Females Identifies Fifteen Novel Skin-Related Trait Associations
Researchers found 15 new genetic links to skin traits in Japanese women.
research Chrousos Syndrome: From Molecular Pathogenesis to Therapeutic Management
The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
research Reproductive Dysfunction in Women with Epilepsy
Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
research Diagnostic Approach to Low-Renin Hypertension
Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
research Finasteride Administration Potentiates the Disruption of Prepulse Inhibition Induced by Forced Swim Stress
Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.
research Endocrine Disorders and Infertility
Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.