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Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.

This study found that the catalytically inactive serine protease CAP1/Prss8 can still induce skin disorders in mice and is subject to inhibition by nexin-1, independent of its catalytic activity.

This study identified a new PNPLA1 mutation in a Spanish family with autosomal recessive congenital ichthyosis.

This study found that quiescence in hair follicle stem cells acts as a tumor suppression mechanism for cutaneous squamous cell carcinoma, with Pten activity necessary to maintain this state.

This study found that after injury, the bone marrow microenvironment's increased Wnt10b expression supports hematopoietic stem cell regeneration by enhancing Wnt signaling, revealing a vital interaction during recovery.

This study observed that the reproductive phenology of Ficus species in Northern Thailand varied seasonally, with female trees producing the most figs during the rainy season, while male trees' fig production peaked earlier.

This review presents an evidence-based algorithm for managing hidradenitis suppurativa in primary care, highlighting the need for more research on treatment effectiveness and the disease's pathogenesis.

This review discusses major advances in understanding inherited hair diseases through genetic research and reports no new clinical results; the authors emphasize the potential for new preventive and therapeutic tools.

This study found that applying topical imiquimod during mid and late telogen in mice activates hair follicle stem cells and influences immune cell infiltration, promoting hair cycle entry independently of Wnt signaling.

This study found that disrupting the inturned gene in developing mouse epidermis halted hair follicle formation due to impaired keratinocyte differentiation, highlighting primary cilia's role in tissue-specific planar cell polarity signaling.

This study found that regio-specific hydroxylation of cyclosporine A in Sebekia benihana is mediated by the cytochrome P450 hydroxylase CYP-sb21, suggesting potential biotechnological applications for hair growth promotion without immunosuppressive effects.

This study found that a gintonin-enriched fraction from ginseng promoted hair growth in mice by stimulating dermal papilla cell proliferation and increasing hair follicles and weight.

This review summarizes existing literature on the safety of commonly used dermatologic medications during pregnancy but does not present new clinical findings, aiming to assist physicians with prescribing decisions.

This study demonstrates that a proposed multi-stage framework improves the accuracy and faithfulness of drug-related responses generated by language models, compared to traditional methods.

In this study, the researchers reported that patient impacts and symptoms of hidradenitis suppurativa, as assessed by HSIA and HSSA measures, are associated with clinical characteristics such as the number of abscesses and inflammatory nodules.

This study identified a cytochrome P450 enzyme, CYP-pa1 from Pseudonocardia autotrophica, as responsible for the specific hydroxylation of cyclosporin A at the 9th N-methyl leucine, suggesting potential for biotechnological applications.

This study found that SYP123 and VAMP727 are involved in the secretion and transport of inner cell wall components, which is crucial for hardening the root hair shank in Arabidopsis.

In this review, the authors concluded that fullerenes and their derivatives are safe for use in cosmetics and could provide antioxidant benefits and other useful properties for cosmetic and dermatological applications.

This article reviews over-the-counter products and active ingredients marketed for hair loss treatment, noting that many lack robust efficacy evidence except for minoxidil, which has temporary effects, and highlights the caution needed when recommending products to pregnant and breastfeeding women.

This study introduced mechanical setups to analyze the mechanical properties of root hairs in Arabidopsis thaliana, finding that axial stiffness primarily relates to tip compression and turgor pressure, confirmed by independent methods adapted from work on animal cells.

This study experimentally validated Lockhart's viscoplastic framework for tip growth in Arabidopsis root hairs by demonstrating alignment with observed growth rates and estimating yield turgor pressure and cell wall viscosity, offering a methodology adaptable to other species and conditions.

In this study, researchers developed innovative mechanical methods to measure the mechanical properties of Arabidopsis thaliana root hairs, concluding that axial stiffness is mainly due to tip compression and influenced by turgor pressure.

This review highlights the potential of extracellular vesicles derived from medicinal plants as therapeutics for diseases such as cancer and inflammation, suggesting they may enhance the clinical use of herbal preparations, despite the challenges posed by extract complexity and individual variability.

In this study, researchers observed that melatonin-mediated LncRNA MTC in Liaoning cashmere goat skin fibroblasts enhances cell proliferation by interacting with the GSTM1 protein, affecting its complex formation with ASK1 and thereby inhibiting apoptosis, which may be relevant for improving cashmere growth.

This review discusses the side effects of gender-affirming hormone therapy and reports no clinical results; it highlights the potential to reduce adverse effect risk factors with healthy eating guidelines.

This study found that overexpressing Rps14 in supporting cells promoted hair cell regeneration in the organ of Corti by facilitating cell proliferation and differentiation.

This study identified peripheral myeloid cells as the earliest dysregulated immune cells in PINK1 KO mice with Parkinson’s-like symptoms following intestinal infections, suggesting that PINK1 regulates gut immune functions linked to early Parkinson’s disease mechanisms.

In this study, researchers identified compound heterozygous variants in the MBTPS1 gene associated with ectodermal dysplasia features in a 14-year-old female, broadening the known disorder spectrum linked to these genetic mutations.

This study found that the PON1 192 R allele was associated with an increased risk of psoriasis and altered lipid profiles in patients from Western Mexico.

In this case report, a 20-year-old male with tricho-rhino-phalangeal syndrome was found to have a de novo frameshift mutation in the TRPS1 gene, highlighting the challenges in diagnosing this rare disorder.