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Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

New JAK inhibitor drugs show promise for treating skin diseases but need more research on safety and effectiveness.

Finasteride 1-mg doesn't harm sperm or pregnancy chances.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Finasteride may affect PNMT, causing side effects.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

More research with diverse participants is needed to determine the effectiveness of photobiomodulation devices for hair loss treatment.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

The document suggests more research is needed to understand the link between baldness and prostate cancer.

Biofeedback treatment for dysfunctional voiding in adults showed no symptom improvement.

Saw palmetto can help with prostate issues and may promote hair growth.

Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.

Fat cells help recruit healing cells and build skin structure during wound healing.

Understanding where cancer cells come from helps create better prevention and treatment methods.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The circadian clock influences the behavior and regeneration of stem cells in the body.