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30-60 / 1000+ resultsresearch Abstract SS02-02: Chemoprevention: Poised for Success
This article reviews pivotal trials and recent findings in chemoprevention for breast, prostate, and colorectal cancers, emphasizing its potential and the importance of further research, public education, and partnerships, but reports no new results.
research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases
This review examines the role of steroidal inhibitors in treating prostatic diseases but presents no new clinical results.
research High Response Rate to Bexxar in Advanced Stage Prior Treatment-Resistant Follicular Lymphoma
This study found that 95% of untreated advanced-stage follicular lymphoma patients responded to a single course of the Bexxar regimen, with 75% achieving complete remission and remaining disease-free for years.
research Triple Hormonal Blockade (ADT3): A Patient’s Perspective
This report suggests that for prostate cancer patients with cardiovascular disease, prescribing the GnRH antagonist degarelix may reduce cardiac events compared to using GnRH agonists, although prescribing should consider potential cardiac risks, particularly in patients with pre-existing conditions or older age.
research MARIO LACOUTURE: How Do I Treat a Patient with Dermatologic Toxicities to EGFR Inhibitors?
This article outlines the author's personal strategies for managing dermatological toxicities, such as acneiform rash and dry skin, associated with EGFR inhibitor therapy; it does not present new research findings.
research Use of Verteporfin with Dermal Wounding to Regenerate New Hair in Androgenetic Alopecia
In this study, two male patients with androgenetic alopecia who had previously undergone hair transplants showed increased hair regrowth after receiving verteporfin injections, with a 63% mean increase in dense donor sites, 38% in thinning areas, but no growth in bald areas.
research 532P Analyses of patient-reported outcomes (PROs) with mirvetuximab soravtansine (MIRV) versus standard chemotherapy in the randomized phase III FORWARD I study in ovarian cancer (GOG 3011)
This study observed that MIRV improved gastrointestinal symptoms and other quality of life measures in patients with platinum-resistant ovarian cancer compared to chemotherapy.
research Sometimes Marketing Efforts by Advocacy Organizations Can Lose Touch with the Nuances of Appropriateness
This article discusses the ethical concerns and implications of a partnership between the National Prostate Cancer Coalition and Viadur, including the perceived endorsement of a specific drug.
research VP-16-213 (etoposide): The mandrake root from Issyk-Kul
This study reports that VP-16-213 (etoposide) shows significant therapeutic activity in several cancers including small cell bronchogenic carcinoma and certain leukemias, with hematologic toxicity being the primary side effect.
research Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells
This study found that valproic acid promoted hair re-growth in C3H mice by activating the Wnt/β-catenin pathway, suggesting its potential as a treatment for alopecia.
research Pertinence d’une chimioprévention à partir de l’étude PCPT
This article discusses the potential of finasteride as a chemopreventive agent for prostate cancer and highlights unresolved issues, but it reports no new research findings.
research Use of Verteporfin to Regrow Hair and Reduce Fibrosis after Transplantation
In this Stanford study, verteporfin was used to promote scarless skin regeneration by inhibiting YAP activity in a 27-year-old female, resulting in increased hair density at the treated site compared to the untreated control.
research Gleason grading controversies: what the chemoprevention trials have taught us
This study found that finasteride reduced prostate cancer incidence by 30%, with no significant difference in Gleason scores compared to placebo after re-evaluation of pathology and extended follow-up.
research Transcutaneous implantation of valproic acid-encapsulated dissolving microneedles induces hair regrowth
This study found that in vivo, a novel microneedle system for valproic acid delivery may improve hair regrowth efficacy by upregulating hair follicle development pathways more effectively than topical application.
research Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations
This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
research ENRIQUECIMENTO AMBIENTAL ASSOCIADO A PROMOÇÃO DO BEM ESTAR PARA CAMUNDONGOS MANTIDOS EM BIOTÉRIOS
This case report from the study describes a dog suffering from dermatophytosis caused by Microsporum canis, presenting with alopecia on the neck and ear, illustrating the zoonotic risk of these fungal infections in both animals and humans, particularly in hot and humid climates.
research Isolation and Characterization of a Fetal-Maternal Microchimeric Stem Cell Population in Maternal Hair Follicles Long after Parturition
In this study, fetal stem cells were identified in adult human hair follicles long after childbirth, indicating potential for autologous therapies due to their pluripotent characteristics.
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
This article describes the efficient synthesis of (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide, a novel topical antiandrogen, with high purity and enantiomeric excess but reports no pharmacological results.
research Alterações dermatológicas em pacientes oncológicos – adultos e crianças
This study created a novel classification for dermatological and cosmiatric changes caused by cancer treatments, categorizing them as triggered, exacerbated, or unrelated to the treatment.
research Tratamento da alopecia areata com corticóide tópico: estudo prospectivo randomizado duplo cego em crianças
This study found no significant difference in the effectiveness of betamethasone dipropionate cream compared to placebo for treating alopecia areata in children, and atopic status did not influence treatment response.
research Hair Growth Activity of Three Plants of the Polynesian Cosmetopoeia and Their Regulatory Effect on Dermal Papilla Cells
In this study, extracts from three Polynesian plants—Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana—were found to increase dermal papilla cell proliferation and modulate hair growth-related gene expression, suggesting potential for stimulating hair growth.
research Differential risk for COVID-19 in the first wave of the disease (February-April 2020) among migrants from several areas of the world living in Alcorcón (Spain): A population-based cohort study
This study found that in Alcorcón, Spain, migrants from Sub-Saharan Africa, the Caribbean, and Latin-America had a higher risk of COVID-19 infection during the first wave compared to Spaniards.
research BENEFÍCIO DO PLASMA SANGUÍNEO NA ESTÉTICA: REVISÃO DA LITERATURA
This review discusses the use of platelet-rich plasma in aesthetic treatments, emphasizing its benefits and potential as a promising and safe alternative for enhancing appearance and self-confidence, without presenting new clinical results.
research Minoxidil tópico o minoxidil oral en la alopecia. ¿Cuál es su elección?
Choose between topical and oral minoxidil for hair growth based on personal tolerance and side effects.
research Grey, curly and short-haired Swiss Holstein cattle show genetic traces of the Simmental breed
This study found that Swiss cattle exhibiting rat-tail syndrome are heterozygous for genetic variants linked to pigmentation and color dilution, likely due to Holstein introgression in the Simmental breed.
research Beneficios y riesgos de los implantes de testosterona en mujeres: revisión sistemática de la literatura
This review concluded that for women, the benefits of testosterone implants are outweighed by risks, with possible higher rates of irreversible adverse effects than previously reported.
research In Vitro Hair Dermal Papilla Cells Induction by Fagraea berteroana, a Tree of the Marquesan Cosmetopoeia (French Polynesia)
This study found that the ethyl acetate extract of Fagraea berteroana fruits and its fraction FEAE-F0 promoted cell proliferation and modulated gene expression in hair follicle cells, suggesting potential for hair growth stimulation.
research EVALUATION OF EFFICACY AND SAFETY OF PLATELET RICH PLASMA (PRP) IN THE TREATMENT OF ANDROGENIC ALOPECIA AND BACTERIAL ULCERATIVE LESION
This study found that PRP therapy was effective and safe for treating androgenic alopecia, promoting 30% hair growth and showing antimicrobial activity against certain bacteria in affected patients.
research Sensitization and Clinically Relevant Allergy to Hair Dyes and Clothes from Black Henna Tattoos: Do People Know the Risk? An Uncommon Serious Case and a Review of the Literature
This review highlights a case of cross sensitization to dyes from temporary henna tattoos and stresses the need for public awareness on the risks associated with these tattoos.