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Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

A natural steroid in the body may protect against eye damage in glaucoma.

Finasteride has a higher risk of reproductive side effects than minoxidil.

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.

A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Key genes can rewire networks, changing skin appendage types.

Methamphetamine affects gene expression in rat whisker follicles, with key genes linked to addiction.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.

The research found that the gene activity in mouse skin stem cells changes significantly as they age.

ceRNA networks offer potential treatments for skin aging and wound healing.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

CRISPR/Cas9 editing in spinach affects root hair growth by altering specific genes.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.

Egyptian Mint effectively kills mosquito larvae and inhibits certain bacteria.