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Brepocitinib 30mg is most effective for moderate-to-severe alopecia areata, but ritlecitinib 50mg may offer a better balance of safety and effectiveness.

The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.

Certain genetic variants and pathways are linked to hair loss.

Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.

Cancer treatments can cause various eye problems, so eye doctors should know how to diagnose and treat these early.

There is no cure for alopecia areata, but treatments like JAK inhibitors show promise.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

RE-ORGA, a Korean herb extract, may help prevent hair loss.

Natural products show promise for new hair loss treatments.

Higher STAT3 levels are found in hair loss areas, but not linked to hair loss severity.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Tofacitinib helped regrow hair in patients with alopecia, with few side effects.

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.

New treatments focusing on immune pathways show promise for stubborn hair loss.

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

Afro-textured hair needs personalized care due to its unique genetic traits.

Personalized treatments for hair loss are becoming more effective by using genetic information.

Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.

Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.

The Naked (N) trait in mice is linked to lower glycine and tyrosine in hair proteins.

Feed restriction in sheep leads to finer wool fibers but may reduce wool quality.

Biotin helps regulate proteins in the blood, which may explain its role in hair growth.

Hair proteins have weak spots in their α-helical segments.

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.

Disulfide bonds in keratin fibers break more easily under stress, especially when wet, affecting fiber strength.