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DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

EGFR cancer drugs often cause a rash, which can lead to distress and isolation, but may also improve outcomes for some cancer patients. Current treatments for the rash are limited, but a compound called menadione shows promise.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Beta-caryophyllene, found in essential oils, helps wounds heal better in multiple ways.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

Follistatin helps hair growth and cycling, while activin prevents it.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Substance from human umbilical cord blood cells promotes hair growth.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.