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Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Targeting colon cancer stem cells might lead to better treatment results.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Auxin and ethylene hormones both work together and against each other to control plant growth.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Different types of skin cells play specific roles in development, healing, and cancer.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Humans lost body hair relatively recently in evolution.

Cathepsin L is essential for normal hair growth and development.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.