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Keratin structure changes during keratinization, but the exact model remains uncertain.

This study provides insight into the specific disulfide bond interactions between keratins and keratin associated proteins, suggesting non-random cysteine interactions crucial for stabilizing hair fiber structure.

This study identified key molecular differences between Long and Short hair type cashmere goats, suggesting hair type differentiation is linked to structural assembly and follicle remodeling.

In this in silico study, researchers analyzed nonsynonymous SNPs in the LIPH gene linked to hypotrichosis and identified three potentially harmful variants (W108R, C246S, and H248N) out of 215 total, using sequence- and architecture-based bioinformatics techniques to differentiate between harmful and benign SNPs.

In this study, hair shafts from trichothiodystrophy patients with ERCC2 mutations revealed abnormal cuticle structures and protein imbalances compared to normal hair shafts.

This study reports the discovery of mutations in the PADI3, TGM3, and TCHH genes as molecular genetic causes of uncombable hair syndrome in children, indicating an autosomal-recessive inheritance pattern.

This study characterized keratin-based biomaterials that self-assemble into hydrogels, demonstrating their potential to achieve hemostasis in a lethal liver injury model through specific biomaterial-receptor interactions.

This study reports various immunophenotypical patterns in apocrine mixed skin tumors, resembling the structures of hair follicles, sebaceous glands, and apocrine glands.

This study presents the first detailed 3D models of the complete K1/K10 keratin dimer and identifies structural features and interactions that may inform understanding of keratin filament assembly.

This narrative review discusses the structure and functions of the skin, focusing on its barrier role, self-repair, thermoregulation, and immune functions, and reports no new experimental results.

This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.

This study found that Wnt ligands from CD133-positive dermal papilla cells are essential for maintaining hair growth by supporting cell signaling between different hair follicle structures.

This study found that hair loss in an Olmsted syndrome mouse model with a Trpv3 mutation was linked to premature keratinocyte maturation, affecting hair follicle structure and function.

This article describes a method using the CUBIC protocol to clarify and visualize molecular and cellular interactions in mouse skin biopsies at single cell resolution, but does not provide new biological findings.

This study investigated the immunohistochemical characteristics of keratin proteins in epidermal appendages, finding variable staining patterns in different skin structures and tumor cells, which suggests differences in keratinization.

This review focuses on the roles of amino acids, peptides, and proteins in cosmetics, highlighting their importance in skin health and their potential for development in personal care products due to their unique properties and biocompatibility.

This study found that genetic variants in the goat KRTAP22-2 gene are associated with the mean fiber diameter of cashmere in Longdong Cashmere goats, suggesting these variants could serve as molecular markers for improving cashmere traits.

This study found that treating hair with ATS, formed from fumaric acid and cysteamine, effectively improved hair quality by increasing moisture content and altering the internal structure of strong curls.

Specific cross-linkages help make hair proteins stable and strong.

This study observed that genetic variation in the ovine KRTAP22-1 gene is linked to increased wool yield and decreased fiber curvature in sheep, indicating its potential use in breeding programs.

Junctional proteins stabilize the inner root sheath and connect the companion layer in human hair.

KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.

This research suggests that both proposed pathways into hair fibers for molecule penetration are valid and complementary, with all fiber structures acting as potential routes for delivering materials.

This review explores the potential of self-amplifying RNA technology for protein replacement therapy in various health disorders but reports no new experimental results, indicating challenges remain for clinical approval.

This study developed a zinc-infused egg white and GelMA hydrogel that enhanced cellular processes crucial for wound healing, including fibroblast proliferation and collagen expression, and demonstrated promising biocompatibility and bioactivity in vivo, suggesting potential effectiveness in repairing damaged tissues.

This article reviews dermatological research on black skin, emphasizing its unique physiological characteristics and common conditions like acne and eczema, and suggests more focus is needed on its structural differences and clinical responses.

This study confirmed the localization of CK19 and vimentin in skin cells, with CK19 linked to hair growth and vimentin stabilizing fibroblast structure.

In this study, researchers developed enzymatic methods to isolate hair cuticle cells and remove the hair cuticle layer, finding that the harvested cuticle cells are thermally more stable and contain different structural proteins compared to descaled hair fibers.

This study found that a bulge stem cell-enriched population from canine hair follicles successfully formed interfollicular epidermis in vitro within two weeks, suggesting potential for regenerative canine skin therapies.

This study found that claudins CLDN1 and CLDN3 are crucial for maintaining proper hair follicle structure in mice, and their dysregulation may lead to telogen hair loss.