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Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Stem cell niches support, regulate, and coordinate stem cell functions.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Fat cells in the skin help start healing and form important repair cells after injury.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Fullerenes show potential in skin care but need more safety research.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.