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This study found that RSL4 in Arabidopsis thaliana regulates genes necessary for root hair elongation by controlling proteins involved in cell signaling, cell wall modification, and secretion.

This animal study found that testosterone treatment increased vas deferens fluid secretion rate in rats, with potential implications for male fertility through the upregulation of AQP-1, 2, and 9 proteins.

This review suggests that the umbilical cord-derived mesenchymal stem cell secretome presents a promising approach for skin regeneration and wound healing due to its multiple therapeutic properties, highlighting its potential over traditional treatments for conditions like chronic wounds and alopecia.

This study suggests that the NGF/TrkA/CREB system plays a crucial role in promoting outer root sheath cell proliferation in cashmere goats, which may aid in marker-assisted breeding.

This study found that specific immune cell phenotypes, particularly CD25 on CD4 Treg cells, were causally linked to androgenic alopecia, suggesting potential targets for immune-based therapies.

This review discusses the therapeutic potential of MSC-derived secretomes for treating degenerative and inflammatory diseases, reporting no new clinical results but highlighting their proposed mechanisms and advantages over direct MSC transplantation.

This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.

In this study, researchers analyzed skin tumors from patients with CYLD cutaneous syndrome and found that loss of CYLD function is linked to changes in cellular signaling pathways, particularly NF-κB signaling, and leads to increased secretion of specific extracellular matrix proteins.

This case report describes a 22-year-old female with pseudoglucagonoma syndrome, where necrolytic migratory erythema resolved after treatment with topical steroids, emollients, and intravenous protein infusions, despite normal glucagon levels and absence of a glucagon-secreting tumor.

Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.

This review discusses the potential of secretome derived from stem cells for treating alopecia areata and reports no new clinical results; the authors suggest the need for further human trials.

This study reports that LL-37 treatment enhances cell proliferation, migration, and secretion of regenerative factors in adipose-derived stem cells, potentially promoting hair growth in vivo.

This study found that PRL-1-overexpressing PD-MSCs reduced adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by secreting IGFBPs and modulating the FAK pathway.

In a laboratory setting, this study found that Biotrinine® dry extract activated hair follicle growth pathways and increased certain growth factor secretions in human dermal papilla cells, suggesting potential benefits for treating chronic hair loss.

This commentary reviews methods for delivering adipose-derived mesenchymal stem cell secretome for facial skin rejuvenation and does not report new clinical results; the authors discuss addressing concerns about administration methods and product characterization.

This study found that combining ISX-9 with mesenchymal stem cells enhanced their ability to reduce inflammation and repair lung damage in an acute lung injury model compared to using the cells alone.

This study found that photobiomodulation-irradiated conditioned medium from human adipose-derived stromal cells enhanced hair growth in mice, suggesting its potential as a treatment for hair loss by increasing growth factor secretion.

This study suggests that proteins CHI3L1 and CXCL5, secreted by recovery-state dermal papilla cells, may promote hair growth by stimulating the proliferation of outer root sheath cells.

This study found that the N-terminal fragment of AIMP1 enhances hair growth and proliferation of hair follicle stem cells in mice, suggesting its potential as a therapeutic peptide for hair loss treatment.

This study suggests that interleukin-1 α influences dermal papilla cell activity by modifying androgen receptor expression and increasing the secretion of several growth factors and cytokines.

This study found that Wnt ligands from CD133-positive dermal papilla cells are essential for maintaining hair growth by supporting cell signaling between different hair follicle structures.

This study investigated the secretome of adipose mesenchymal stem cells and fibroblasts used in skin care products, finding 16 therapeutic pathways involving numerous signaling mechanisms, which may offer skin benefits through anti-inflammatory and regenerative effects.

This study suggests that IL-1β produced by dermal papilla cells, regulated by protein kinase C, may inhibit human hair follicle growth through paracrine signaling.

The T-zone on the face has more androgen receptors and produces more oil than the U-zone.

This review discusses the mechanisms of zinc transport, its role in human health, and the effects of zinc imbalance, without reporting new results.

This study identified a novel skin site called the follicular epidermis that is prone to cancer, with unique Axin2+ stem cells regulating its homeostasis. The findings suggest current therapeutic approaches may need reconsideration due to new insights into obstruction mechanisms at this site.

Melatonin affects specific gene patterns and biological processes in goat hair growth.

This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.

This review discusses the unique features of dermal white adipose tissue, its interaction with hair follicles, and its role in skin physiology, reporting no new experimental findings.

This review summarizes the recent advances in molecular mechanisms influencing tissue sensitivity to glucocorticoids, emphasizing novel mutations and new information on the glucocorticoid receptor's circadian rhythm and ligand-induced repression, but reports no new results.