research Adenovirus-Mediated Wnt10b Overexpression Induces Hair Follicle Regeneration
Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.
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research Pitx2, A β-Catenin-Regulated Transcription Factor, Regulates The Differentiation Of Outer Root Sheath Cells Cultured In Vitro
Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
research ILK Modulates Epithelial Polarity and Matrix Formation in Hair Follicles
ILK is essential for proper hair follicle development and structure.
research Expression of Concern: Potential Risk for Developing Severe COVID-19 Disease Among Anabolic Steroid Users
Anabolic steroid users may face higher risk of severe COVID-19.
research Generation of Tβ4 Knock-In Cashmere Goat Using CRISPR/Cas9
Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
research Nuclear Factor (Erythroid-Derived 2)-Like-2 Pathway Modulates Substance P–Induced Human Mast Cell Activation and Degranulation in the Hair Follicle
Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
research Thy1 Marks a Distinct Population of Slow-Cycling Stem Cells in the Mouse Epidermis
A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
research Alpha-Parvin Is Required for Epidermal Morphogenesis, Hair Follicle Development, and Basal Keratinocyte Polarity
α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
research Analysis of LncRNA-mRNA Co-Expression Profiles in Patients With Polycystic Ovary Syndrome: A Pilot Study
Different types of RNAs are found in varying amounts in patients with Polycystic Ovary Syndrome, suggesting they could be important in the disease's development and potentially used as disease markers.
research The Developmental and Molecular Requirements for Ensuring That Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation
Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
research Cardiometabolic Risk Factors in Women with Non-Classic Congenital Adrenal Hyperplasia
Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.
research Isotretinoin Treatment Upregulates the Expression of P53 in the Skin and Sebaceous Glands of Patients with Acne Vulgaris
Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.
research Backhousia Citriodora Leaf Extract: A New Active Solution to Control Hyper-Seborrhea for Multi-Ethnic Skins
Backhousia citriodora leaf extract effectively reduces oily skin across different ethnic groups.
research Hair Follicle Stem Cells: A New Arena
Hair follicle stem cells have significant potential for treating various disorders.
research Live Imaging of Keratin Network in Stratum Granulosum Reveals Dynamic Cytoskeletal Changes During Cornification in Mice In Vivo
The keratin network in mouse skin changes during cornification and affects the skin's protective barrier.
research Does Mitochondrial Dysfunction Drive Immune Privilege Collapse in Lichen Planopilaris Pathogenesis?
Mitochondrial dysfunction may contribute to chronic inflammation and immune system issues in Lichen planopilaris.
research Clinical Snippets: R-Spondin2 Amplifies Wnt Signaling for Hair Growth, Gene Expression Differences in Balding Scalp, IKB Regulates hBD2 in Psoriasis, ß-Defensin Gene Cluster and Hidradenitis Suppurativa, Autoantigen Epitopes in Alopecia Areata
New treatments for hair growth and psoriasis may be possible, and gene differences could affect baldness and the severity of skin conditions.
research Skin Melanocytes: Biology and Development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins
Hair and nail cells share similar proteins, indicating a common differentiation pathway.
research The Circadian Molecular Clock Creates Epidermal Stem Cell Heterogeneity
The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
research Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome
Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
research Eclipta Alba Extract With Potential For Hair Growth Promoting Activity
Eclipta alba extract may help hair grow similarly to Minoxidil.
research Quantitative Single-Cell Approaches to Stem Cell Research
New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.
research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research Ferreting Out Stem Cells From Their Niches
New methods have greatly improved our understanding of stem cell behavior and roles in the body.
research Diagnosis of Hyperandrogenism: Biochemical Criteria
The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
research Epidermal Stem Cells: Practical Perspectives and Potential Uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research Skin Disorders in Parkinson’s Disease: Potential Biomarkers and Risk Factors
Certain skin conditions may indicate or increase the risk of Parkinson's disease.
research Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Mutations in the Keratin 85 (KRT85/hHb5) Gene Underlie Pure Hair and Nail Ectodermal Dysplasia
Mutations in the KRT85 gene cause hair and nail problems.