research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
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research Overexpression of Smad7 Results in Severe Pathological Alterations in Multiple Epithelial Tissues
Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
research The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain
The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research Loss of Epidermal Evi/Wls Results in a Phenotype Resembling Psoriasiform Dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research Defining the Localization and Molecular Characteristics of Minor Salivary Gland Label-Retaining Cells
The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
research The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia
Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.
research Age-Related Changes in Female Scalp Dermal Sheath and Dermal Fibroblasts: How the Hair Follicle Environment Impacts Hair Aging
Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.
research Fibroblasts Become Fat to Reduce Scarring
Turning scar-forming cells into fat cells can reduce scarring.
research Strategies for Improved Hair Binding: Keratin Fractions and the Impact of Cationic Substructures
Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
research Induction of Autophagy Improves Skin and Hair Conditions in Dogs with Underlying Diseases
Activating autophagy in dogs with certain diseases improves their skin and hair.
research Evaluation of Anti-Hair Loss Shampoo Through In Vitro Activity in Human Hair Follicle Dermal Papilla Cells and Sensorial Study
The anti-hair loss shampoo effectively promotes hair growth and improves hair quality.
research Specific Citrullination Causes Assembly of a Globular S100A3 Homotetramer
A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.
research Androgens Modulate Keratinocyte Differentiation Indirectly Through Enhancing Growth Factor Production From Dermal Fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
research EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner
EGFR helps control how hair grows and forms without needing p53 protein.
research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin
PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
research Mammalian Keratin-Associated Proteins (KRTAPs) Subgenomes: Disentangling Hair Diversity and Adaptation to Terrestrial and Aquatic Environments
Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.
research Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 21 in Fond Memory of Dr. Peter Steinert
A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.
research Mutations in the Helix Termination Motif of Mouse Type I IRS Keratin Genes Impair the Assembly of Keratin Intermediate Filament
Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.
research Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines
Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.
research Characterization of the Epidermal-Dermal Junction in hiPSC-Derived Skin Organoids
The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
research Hipsc-Derived Skin Organoids as Tools for Disease Modelling: Characterization of the Epidermal-Dermal Junction
Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.
research Epidermal Patterning and Induction of Different Hair Types During Mouse Embryonic Development
Different body areas in mice produce different hair types due to interactions between skin layers.
research Caspase-1 Level Is Higher in the Scalp in Androgenetic Alopecia
Higher caspase-1 levels found in balding scalps; reducing it may help treat hair loss.
research Alpha-Parvin Is Required for Epidermal Morphogenesis, Hair Follicle Development, and Basal Keratinocyte Polarity
α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
research Nestin as a Marker of Unipotent Embryonic and Adult Progenitors Differentiating into an Epithelial Cell Lineage of the Hair Follicles
Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.
research Microinjury-Induced Tumor Necrosis Factor-Alpha Surge Stimulates Hair Regeneration in Mice
Minor injuries to hair follicles can stimulate hair growth in mice by increasing a specific protein.
research Nestin as a Marker of Unipotent Epithelial Progenitor Cells Differentiating into Outer Root Sheath Keratinocytes in Embryonic and Adult Hair Follicles
Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
research A Novel Animal Model of Desmoglein 1 (Dsg1) Deficiency Reveals an Essential Role for Dsg1 in Epidermal Barrier Formation
Dsg1 is essential for maintaining a healthy skin barrier in mice.
research Peer Review of Human Hair Shaft Proteomic Profiling: Individual Differences, Site Specificity, and Cuticle Analysis
The research found that people's hair proteins vary, especially by ethnicity and body part, which could help identify individuals in forensic science.