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ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

Topical metformin helped regrow hair in two women with a hard-to-treat scarring hair loss condition.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Iron deficiency may contribute to hair loss.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.

Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Plasmalogens activate a channel in cells that may stimulate hair growth.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Phloroglucinol may help improve hair loss by promoting hair growth and reducing oxidative stress.

A new gene mutation causes insulin resistance in a girl and her mother.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Auxin and ethylene hormones both work together and against each other to control plant growth.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.