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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

COVID-19 vaccination may trigger lupus in some people.

Most pregnancies with SLE resulted in intrauterine growth restriction (IUGR).

A Doberman Pinscher had a rare form of autoimmune disease causing hair loss and other severe symptoms.

New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.

Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.

Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.

Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

Follicle Stimulating Hormone is important for fertility.

Human hair loss may have evolved to help increase brain size.

Zinc can help with some skin problems, but its effectiveness varies depending on the condition.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Zinc can be a helpful secondary treatment for certain skin conditions, but more research is needed to guide its use.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

NKG2D gene polymorphism doesn't affect SLE risk but may influence symptoms like rash and hair loss.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.

COVID-19 may harm male fertility and damage the reproductive system.