8 citations,
December 2015 in “The Journal of Physiology” The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.
3 citations,
December 2022 in “npj Regenerative Medicine” HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
September 2017 in “Journal of Investigative Dermatology” Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.
August 2015 in “Free Radical Biology and Medicine” The document concludes that the discussed biological mechanisms and potential therapies are not related to hair loss or hair growth.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Targeted cancer therapies can cause skin side effects, but activating SOS in the skin may help reduce them.
60 citations,
June 1997 in “Journal of The American Academy of Dermatology” Apoptosis is crucial for healthy skin and treating skin diseases.
7 citations,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
23 citations,
December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
3 citations,
January 2019 in “International Journal of Trichology” The balance of thiol-disulfide in women with hair loss is affected but not damaged.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
35 citations,
January 2013 in “The Journal of experimental medicine/The journal of experimental medicine” CD98hc's role in skin health decreases with age.
1 citations,
January 2021 in “Journal of biological chemistry/The Journal of biological chemistry” FLCN helps control iron levels in cells.
September 2023 in “Nature communications” Alk1 in specific cells is crucial for proper nerve branching and hair function.
84 citations,
December 2017 in “EMBO Reports” Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
6 citations,
November 2021 in “Frontiers in immunology” STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
May 2018 in “Journal of Investigative Dermatology” DNMT3A is crucial for healthy skin and hair growth.
April 2017 in “Journal of Investigative Dermatology” Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
254 citations,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
107 citations,
August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
65 citations,
February 2017 in “Pflügers Archiv - European Journal of Physiology” Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
50 citations,
September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
50 citations,
December 2013 in “Stem Cells” Stem cell niches are adaptable and key for tissue maintenance and repair.
24 citations,
May 2016 in “Stem Cell Reviews and Reports” The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
19 citations,
February 2018 in “Nutrients” Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.
12 citations,
June 2020 in “Frontiers in Cell and Developmental Biology” The PP2A-B55α protein is essential for brain and skin development in embryos.
10 citations,
December 2015 in “International Journal of Molecular Sciences” PDCD4 is important for controlling skin cell growth and healing.
10 citations,
November 2015 in “Plant Foods for Human Nutrition” Hibiscus petals helped control blood sugar and improve liver and pancreas health in diabetic rats.
7 citations,
September 2019 in “Journal of Cellular Physiology” Akt2 protein is essential for normal cell division in early mouse embryos.
7 citations,
November 2014 in “Histochemistry and Cell Biology” The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.