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All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Lower SHBG levels may increase the risk of PCOS.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Wool follicles are complex, involving interactions between different cell types and structures.

Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Sponge helps heal wounds faster with less inflammation and better skin/hair growth.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Hair shedding is an active process that could be targeted to treat hair loss.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Minoxidil boosts hair growth by activating PGHS-1.

Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Some common medications can harm male fertility, but many effects can be reversed.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.

Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.