research A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling
Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.
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research Aberrant Wnt Signaling Induces Comedo-Like Changes in the Murine Upper Hair Follicle
Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
research Camellia Seed Cake Extract Supports Hair Growth by Abrogating the Effect of Dihydrotestosterone in Cultured Human Dermal Papilla Cells
Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.
research 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA)
3D cell cultures are better for testing hair growth treatments than 2D cultures.
research MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata
miR-199a-3p controls hair growth and is linked to alopecia areata.
research Nigella Sativa And Its Nano-Mediated Approach Toward Management Of Neurodegenerative Disorders: A Review
Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.
research The Hair Growth-Promoting Effect of Gardenia Florida Fruit Extract and Its Molecular Regulation
Gardenia florida fruit extract may help hair grow and needs more research to understand how.
research Exosomes Derived From Mouse Vibrissa Dermal Papilla Cells Promote Hair Follicle Regeneration During Wound Healing By Activating Wnt/β-Catenin Signaling Pathway
Mouse cell exosomes help hair regrowth and wound healing by activating a specific signaling pathway.
research Safety of Antiandrogens for the Treatment of Female Androgenetic Alopecia with Respect to Gynecologic Malignancies
Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.
research MSC-Derived Exosomes Protect Auditory Hair Cells From Neomycin-Induced Damage Via Autophagy Regulation
Tiny particles from stem cells can help protect ear cells from antibiotic damage by helping cells remove damaged parts.
research Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter
Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
research Nanotechnology-Based Techniques for Hair Follicle Regeneration
Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
research Life Sciences Discovery And Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research Water Extract of Cacumen Platycladi Promotes Hair Growth Through the Akt/GSK3β/β-Catenin Signaling Pathway
Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.
research Directed Elimination of Senescent Cells by Inhibition of BCL-W and BCL-XL
Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
research Intracrine Androgen Biosynthesis, Metabolism, and Action Revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Beta-Catenin-Mediated Hair Growth Induction Effect of 3,4,5-Tri-O-Caffeoylquinic Acid
3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.
research Establishment and Characterization of a Radiation-Induced Dermatitis Rat Model
Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research MTORC1 Activity Negatively Regulates Human Hair Follicle Growth and Pigmentation
High mTORC1 activity slows hair growth and causes it to lose color.
research Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway
research Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium Ascalonicum L.) Extract
Shallot extract may help with hair growth and treating hair loss.
research 5-Bromo-3,4-Dihydroxybenzaldehyde Promotes Hair Growth Through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells
5-Bromo-3,4-dihydroxybenzaldehyde could potentially help hair growth by activating certain cell pathways and inhibiting others.
research Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair Follicle Neogenesis
The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
research Hair Follicles as a Critical Model for Monitoring the Circadian Clock
Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.
research Recent Advances in Exosomal Non-Coding RNA-Based Therapeutic Approaches for Photoaging
New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.
research Cell Surface B2m-Free Human Leukocyte Antigen Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA?
B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.
research The Potential Role of hsa_circ_0001079 in Androgenetic Alopecia via Sponging hsa-miR-136-5p
hsa_circ_0001079 may help diagnose and treat hair loss.
research IGF1 and BM-MSC Incorporating Collagen-Chitosan Scaffolds Promote Wound Healing and Hair Follicle Regeneration
Adding insulin-like growth factor 1 and bone marrow-derived stem cells to a collagen-chitosan scaffold helps wounds heal faster and regrows hair follicles.