research The Effect of Finasteride on the Male Rat Brain
Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.
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research Impact of Thyroid Dysfunction on Hair Disorders
Thyroid problems can cause hair loss and change hair texture.
research Triton Modified Polyethyleneimine Conjugates Assembled With Growth Arrest-Specific Protein 6 for Androgenetic Alopecia Transdermal Gene Therapy
The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.
research Assessment of Cardiovascular Risk in Patients with Androgenetic Alopecia Using High-Sensitivity C-Reactive Protein and Lipoprotein A
People with androgenetic alopecia have a higher risk of heart disease.
research Platelet-Rich Plasma for Hair Loss
Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.
research Transgenerational Transmission of Reproductive and Metabolic Dysfunction in Male Progeny of Polycystic Ovary Syndrome
Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.
research Downregulation of mRNAs Encoding Keratin-Associated Proteins in the Tongue of Mice Fed a High-Fat Diet
A high-fat diet may weaken tongue structure by reducing certain protein genes.
research Using the Frog Embryonic Epidermis as a Model to Study Desmosome Function During Development
Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the Ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine
Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
research Clinical Application of Nonantibiotic Macrolides for Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases
Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
research Epimorphic Regeneration in Mice Is p53-Independent
Mice can regenerate ear tissue without the p53 protein.
research Novel Effect of Sildenafil on Hair Growth
Sildenafil, often used for erectile dysfunction, may help hair growth.
research Novel ALK5 Inhibitor TP0427736 Reduces TGF-β Induced Growth Inhibition in Human Outer Root Sheath Cells and Elongates Anagen Phase in Mouse Hair Follicles
TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.
research Septin4 Promotes Cell Death in Human Colon Cancer Cells by Interacting with BAX
Septin4 helps kill colon cancer cells by working with the protein BAX.
research Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19
Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
research Growth Hormone Deficiency with Late-Onset Hypothalamic Hypoadrenocorticism Associated with Respiratory and Renal Dysfunction: A Case Report
A woman with childhood growth hormone deficiency had multiple hormone deficiencies and developed serious lung and kidney problems later in life.
research Col4a2-eGFP Mouse Model Reveals the Molecular and Functional Dynamics of Basement Membrane Remodelling in Hair Follicle Morphogenesis
Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
research Dysregulation of Grainyhead-Like 3 Expression Causes Widespread Developmental Defects
Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
research Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis
Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
research FOXO1, TGF-β Regulation and Wound Healing
FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.
research Beyond Testosterone Cypionate: Evidence Behind the Use of Nandrolone in Male Health and Wellness
Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
research Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome
The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.
research Fisetin Promotes Hair Growth by Augmenting TERT Expression
Fisetin, a type of polyphenol, may help hair grow by increasing certain protein activities in cells.
research Finasteride
Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
research Testosterone in Women: Measurement and Therapeutic Use
Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.
research An Updated Review of the Sebaceous Gland and Its Role in Health and Diseases Part 1: Embryology, Evolution, Structure, and Function of Sebaceous Glands
Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.
research Can Male-Pattern Baldness Be Prevented? Promising Results from a Study on Treating Male-Pattern Baldness with Oral Finasteride
Finasteride may increase hair growth and prevent baldness in men, but can cause sexual side effects.
research First Reboxetine Trial Results Reported
Finasteride increased hair count and regrowth in men with hair loss but also caused more sexual side effects than placebo.
research Severe Metabolic Disorders Coexisting With Werner Syndrome: A Case Report
A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.