research Adipose and Hair Function: An Apparent Connection
Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.
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research Expression of AKT1 Along with AKT2 in Granulosa-Lutein Cells of Hyperandrogenic PCOS Patients
The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Skin Metabolism in Obesity: A Narrative Review
Obesity harms skin health by causing inflammation and delayed wound healing.
research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research Evaluation of Some Biochemical Markers in Alopecia Areata
People with alopecia areata have different blood markers that suggest inflammation and immune system issues compared to healthy individuals.
research Overview of Lichen Planopilaris: Diagnosis and Treatment
Lichen Planopilaris is a hair loss condition best treated early with various medications, including hydroxychloroquine, to prevent permanent baldness.
research Expert Medical Testimony on Penicillamine Side Effects
Penicillamine can cause taste problems due to copper loss, which can be fixed with copper or zinc supplements.
research Biotin: Essential Vitamin for Lipid Metabolism and Cellular Functions
People need different amounts of biotin based on age and it's important for health, with many foods providing enough.
research Biotin: Daily Intake Requirements, Sources, and Deficiency Effects
People need different amounts of biotin based on age, and not getting enough can cause health problems.
research Editorial Board: Importance of Biotin in Metabolic Processes
Biotin is important for metabolism, with specific daily intake recommendations, and deficiency can cause health problems.
research A Novel Animal Model of Desmoglein 1 (Dsg1) Deficiency Reveals an Essential Role for Dsg1 in Epidermal Barrier Formation
Dsg1 is essential for maintaining a healthy skin barrier in mice.
research Is Intrafollicular Autophagy an Essential Mechanism That Permits Human Hair Follicles to Remain in Prolonged Anagen In Vivo?
Autophagy, a cell recycling process, is crucial for prolonged hair growth and could be a potential target for treating hair growth disorders.
research Connexin 43 Expression in the Testes During Postnatal Development of Finasteride-Treated Male Rat Offspring
Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
research Skin Fragility, Diffuse Ecchymosis, and Blisters on a Yellowish Waxy Base
A woman's skin symptoms led to a diagnosis of systemic AL amyloidosis, but she died from sepsis shortly after.
research The Biomedical Role of Zinc in the Functioning of the Human Organism
Zinc is essential for many body functions and imbalances can lead to health problems.
research Cutaneous T-Cell Lymphoma
The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.
research The Editor's Choice: Summary of Studies on Skin and Hair Conditions
UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.
research Mechanisms of Cutaneous Adverse Events During Targeted Cancer Therapy
Targeted cancer therapies can cause skin side effects, but activating SOS in the skin may help reduce them.
research Three-Dimensional Imaging of Tight Junction Network Across Multiple Layers of Human Epidermis by Array Tomography Using Backscattered Electron-Mode Scanning Electron Microscopy
The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.
research Deciphering the Molecular Mechanisms of Stem Cell Dynamics in Hair Follicle Regeneration
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
research Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice
Mice with autoimmune hair loss showed signs of heart problems.
research Protein Kinase C Downregulation Upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease
Rapamycin treatment helps reduce brain inflammation and symptoms of mitochondrial disease by blocking specific pathways in mice.
research Dysfunction of Hair Follicle Mesenchymal Progenitors Is Associated with Age-Related Hair Loss
Age-related hair loss is linked to the decline and dysfunction of hair follicle stem cells.
research Does Mitochondrial Dysfunction Drive Immune Privilege Collapse in Lichen Planopilaris Pathogenesis?
Mitochondrial dysfunction may contribute to chronic inflammation and immune system issues in Lichen planopilaris.
research Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients
Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
research Erectile Dysfunction in Young Men: A Review of Prevalence and Risk Factors
Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.
research Endothelial Dysfunction in PCOS: Role of Obesity and Adipose Hormones
Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.
research Reproductive Dysfunction in Women With Epilepsy: Recommendations for Evaluation and Management
Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.
research The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer, and Depression
5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.