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Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Targeting TGFβ can improve skin immunity in older people.

Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.

Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.

Non-coding RNAs could help detect and treat radiation damage.

GRHL3 is important for controlling gene activity in skin cells during different stages of their development.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Future clinical uses of Intense Pulsed Light (IPL) are likely to grow and become more effective with new advancements and combined treatments.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

The right amount of retinoic acid is essential for normal hair growth and development.

3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.

Combined arsenic and low oxygen stress alters root growth to help plants absorb nutrients.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Some patients using cold caps to prevent hair loss from chemotherapy got mild scalp injuries similar to frostbite.

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

Skin organoids from stem cells could better mimic real skin but face challenges.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.