research Characterization of the Cysteine-Rich Calcium-Binding S100A3 Protein from Human Hair Cuticles
Scientists found out how a specific protein in human hair cuticles behaves and is structured.
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research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
Vitexin Compound 1 may help reduce skin aging caused by UVA light.
research Mu-Crystallin, Thyroid Hormone-Binding Protein, Is Expressed Abundantly in the Murine Inner Root Sheath Cells
μ-Crystallin may help hair growth by affecting thyroid hormone levels in mouse hair follicles.
research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
research LncRNA018392 Promotes Proliferation of Liaoning Cashmere Goat Skin Fibroblasts Through Up-Regulation of CSF1R by Binding to SPI1
A specific RNA helps increase the growth of skin cells in Liaoning cashmere goats by working with a protein to boost a growth-related gene.
research Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility
Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
research Immunolocalization of Enzymes, Binding Proteins, and Receptors Sufficient for Retinoic Acid Synthesis and Signaling During the Hair Cycle
Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.
research Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research GLI2-Specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
GLI2 increases follistatin production in human skin cells.
research Molecular Modeling of Hair Keratin/Peptide Complex: Using MM-PBSA Calculations to Describe Experimental Binding Results
Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
research Maintenance of Epidermal Progenitor Function Through the mRNA Degradation and Translation Pathways
The protein DDX6 helps keep skin cells renewing properly by controlling the production of certain other proteins and breaking down those that cause cells to mature too quickly.
research Modulation of YBX1 Phosphorylation Determines Epidermal Stem Cell Function
Changing YBX1 protein activity affects skin stem cell function and aging.
research CCN2 Modulates Hair Follicle Cycling in Mice
The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
research The Variable Cell
Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
research The Negative Regulator CXXC5: Making WNT Look a Little Less Disheveled
CXXC5 is a protein that prevents hair growth and could be a target for hair loss treatment.
research Management of Neonates and Children with Male Pseudohermaphroditism
Individuals with male pseudohermaphroditism often do better raised as females with early surgery.
research Impact of Treatment with Rosiglitazone or Metformin on Biomarkers for Insulin Resistance and Metabolic Syndrome in Patients with Polycystic Ovary Syndrome
Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.
research Low Anabolic Profile in Assessing a Patient’s Overall Hair Loss
Some supplements and hormones can increase hair loss by raising DHT levels.
research Atypical Formations of Gintonin Lysophosphatidic Acids as New Materials and Their Beneficial Effects on Degenerative Diseases
New ginseng compounds may help treat degenerative diseases.
research An Unusual Presentation of Vitamin D Dependent Rickets Type 2 with Low 25(OH)D3 Levels and Alopecia: A Case Report of Two Siblings
Two siblings with a rare type of rickets and hair loss had low vitamin D levels, which is not typical for their condition.
research Attenuation of 5α-Reductase-Mediated Progesterone Metabolism Promotes Differentiation of Human Endometrial Stromal Cells for the Establishment of Pregnancy
Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.
research Genetics of Alopecia
Different genes are linked to various types of hair loss.
research Treatment of Alopecia Areata: What Is New on the Horizon?
New treatments for alopecia areata may target specific immune cells and pathways involved in hair loss.
research Identification of Telogen Markers Underscores That Telogen Is Far from a Quiescent Hair Cycle Phase
Telogen is an active phase with important biological processes, not a resting phase.
research Prevalence of Polycystic Ovaries in Women with Self-Reported Symptoms of Oligomenorrhoea and/or Hirsutism: Northern Finland Birth Cohort 1966 Study
Women with irregular periods and/or excessive body hair are more likely to have polycystic ovaries, and this condition is linked to higher health risks.
research Effect of Retinoids on Follicular Cells
Retinoids can change the hair growth cycle by extending the growth phase and shortening the rest phase.
research IGFBP-rP1 Is a Potential Therapeutic Target in Androgenic Alopecia
IGFBP-rP1 could be a new treatment for a common type of hair loss.
research Two Novel MBTPS2 Missense Mutations Impairing S2P Proteolytic Activity Lead to IFAP Syndrome With New Phenotypic Anomalies
New mutations in MBTPS2 reduce its function and cause IFAP syndrome with unusual symptoms.
research Human Umbilical Cord Blood Mesenchymal Stem Cells Engineered to Overexpress Growth Factors Accelerate Outcomes in Hair Growth
Modified stem cells from umbilical cord blood can make hair grow faster.
research Androgens Modulate Keratinocyte Differentiation Indirectly Through Enhancing Growth Factor Production From Dermal Fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.