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Research 30 of 629
- Escin Activates Canonical Wnt/β-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3β in Cultured Human Dermal Papilla Cells
- Dihydrotestosterone induces p27 degradation via direct binding with SKP2 in ovarian and breast cancer
- Proteolysis‐targeting chimeras in cancer therapy: Targeted protein degradation for next‐generation treatment
- Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex
- Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases
- 1430 Autophagy controls the protein composition of hair shafts
- Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys cahirinus and Scarring Mus musculus
- Abstract 5561: 20(S)-Protopanaxadiol-aglycone downregulates full-length and ligand-independent splice variants of androgen receptor
- Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism
- Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions
- Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing β-Catenin
- Protein degradation: expanding the toolbox to restrain cancer drug resistance
- PROTACs in cancer therapy: targeted degradation of GPX4, PARP and epigenetic regulators
- N-(3,5-Dimethylphenyl)-3-Methoxybenzamide (A3B5) Targets TRP-2 and Inhibits Melanogenesis and Melanoma Growth
- Clinical Translation of Targeted Protein Degraders
- PROTACs: A novel strategy for cancer drug discovery and development
- Advancing Design Strategy of PROTACs for Cancer Therapy
- Spironolactone and XPB: An Old Drug with a New Molecular Target
- Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation
- Smad7-Induced β-Catenin Degradation Alters Epidermal Appendage Development
- Sulforaphane promotes murine hair growth by accelerating the degradation of dihydrotestosterone
- The antimycotic agent clotrimazole inhibits melanogenesis by accelerating ERK and PI3K-/Akt-mediated tyrosinase degradation
- <i>De novo</i> designed bifunctional proteins for targeted protein degradation
- Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
- NF-κB in biology and targeted therapy: new insights and translational implications
- Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching (FRAP) Is an Integrated Measure of Receptor Function
- Lysocellin, a metabolite of the novel drug ‘alopestatin’, induces G1 arrest and prevents cytotoxicity induced by etoposide
- Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection
- Targeted protein degradation of Wnt/β-catenin signaling pathway: an effective strategy for cancer therapy
- Emerging Strategies in Smart Nano-PROTAC for Stimuli-Responsive Protein Degradation and Precision Cancer Therapy