research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
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research Intraoperative Floppy-Iris Syndrome and Finasteride Intake
Finasteride may cause floppy-iris syndrome during cataract surgery, so check patients' medical history.
research The Placebo Effect And Randomized Trials: Analysis Of Conventional Medicine
The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.
research FCE 28260, A New 5α-Reductase Inhibitor: In Vitro and In Vivo Effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research Trends in 5-Alpha Reductase Inhibitor Use Before and After the Food and Drug Administration Safety Warning
Prescriptions for 5-alpha reductase inhibitors dropped significantly after the FDA's safety warning, especially for men with benign prostatic hyperplasia.
research The Relationship of Depression, Alcohol, and Marijuana with Treatment for LUTS/BPH
Men with depression and marijuana usage are more likely to be treated for lower urinary tract symptoms/benign prostatic hyperplasia.
research Structure of Human Type II 5 Alpha-Reductase Gene
The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
research Incidence of Serious Infectious Events with Methotrexate Treatment: Meta-Analysis of Randomized Controlled Trials
Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.
research Association of Frailty Index with Clinical Benign Prostatic Hyperplasia Progression and Serious Adverse Events: The MTOPS Trial
Frailer men have a higher risk of worsening prostate problems and serious health events needing hospital care.
research Marijuana, Alcohol, Erectile Dysfunction, And Depression: Epidemiologic Correlations With Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms
Marijuana use is linked to higher chances of needing treatment for urinary symptoms in men over 40.
research Antiandrogens: Clinical Applications
Antiandrogens help treat hormone-related conditions in both men and women.
research Endocrine Treatment of Benign Prostatic Hypertrophy: Current Concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
research Can Long-Term LUTS/BPH Pharmacological Treatment Alter the Outcomes of Surgical Intervention?
Long-term medication for enlarged prostate might not clearly affect the timing or outcomes of later surgery.
research Clinical Relevance of Testosterone and Dihydrotestosterone Metabolism in Women
Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
research Post-Finasteride Syndrome: A Surmountable Challenge for Clinicians
Finasteride can cause serious side effects in some men, needing more research for treatment.
research Clinical Effects and Economic Impact of Dutasteride and Finasteride Therapy in Italian Men with Lower Urinary Tract Symptoms
Dutasteride reduces hospitalization and prostate cancer risk compared to finasteride, potentially offsetting its higher cost.
research Faculty Opinions Recommendation of Post-Finasteride Syndrome: A Surmountable Challenge for Clinicians
Clinicians need to better understand and treat Post-finasteride syndrome.
research Post-Finasteride Syndrome: When Will We Get the Courage to Fight the Dictating Pharma Industry Despite Awareness of Sexual, Neurological, and Metabolic Side Effects in Young Men for Over a Decade
Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
research The Pathophysiology of Delayed Ejaculation
Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.
research The Prevention of Benign Prostatic Hyperplasia (BPH)
A vaccine may prevent benign prostatic hyperplasia (BPH).
research The Association of Male Pattern Baldness in Men with Benign Prostatic Hyperplasia
Men with male pattern baldness are more likely to have benign prostatic hyperplasia.
research Efficacy, Safety, and Adverse Effects of Finasteride and Dutasteride in Treating Benign Prostatic Hyperplasia: A Retrospective Cohort Study
Finasteride and dutasteride are equally effective and safe for treating BPH.
research May Patients Receiving 5-Alpha-Reductase Inhibitors Be at Higher Risk of COVID-19 Complications?
Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.
research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research The Post-Finasteride Syndrome: An Overview
Finasteride can cause side effects, some lasting after treatment ends, and may lead to severe depression or suicidal thoughts.
research Clinics in Diagnostic Imaging: A 55-Year-Old Man with Benign Prostatic Hyperplasia and Extraperitoneal Bladder Perforation
A bladder rupture from prostate treatment was healed with catheterization and antibiotics.
research Incidence of Type 2 Diabetes Mellitus in Men Receiving Steroid 5α-Reductase Inhibitors: Population-Based Cohort Study
Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
research Administration of Caesalpinia Bonduc Seed Extracts Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia in Male Wistar Rats
Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
research Inhibitory Effects of Pueraria Mirifica Aqueous Extracts on 5α-Reductase and Prostate Histomorphometry in Testosterone-Induced Benign Prostatic Hyperplasia Sprague Dawley Rats
Pueraria mirifica extract may help treat benign prostatic hyperplasia.
research Prevalence of Metabolic Syndrome and Its Components Among Men With and Without Clinical Benign Prostatic Hyperplasia: A Large, Cross-Sectional, UK Epidemiological Study
Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.