November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
2 citations,
January 2019 in “BMC Cancer” Baldness may lower the risk of testicular cancer.
4 citations,
January 2015 in “Pharmacology” Serenoa repens may cause early puberty and should be used cautiously in children.
25 citations,
May 2014 in “Facial Plastic Surgery” PRFM may help treat hair loss, especially in mild cases.
16 citations,
September 2018 in “Journal of Molecular Liquids” The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.
12 citations,
October 2018 in “Aging male/The aging male” Higher BMI and lower testosterone are linked to more aggressive prostate cancer.
127 citations,
May 2004 in “PubMed” Finasteride may help some male chronic pelvic pain patients, but more research needed.
105 citations,
January 2004 in “The Journal of Urology” Finasteride improves chronic pelvic pain, saw palmetto doesn't.
April 2024 in “Nigerian Postgraduate Medical Journal” Androgenetic alopecia is a common hair loss condition influenced by various factors and linked to psychosocial and cardiovascular issues.
20 citations,
December 1994 in “Fertility and sterility” Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.
October 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” DA-9401 can protect against finasteride-induced reproductive damage in rats.
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
30 citations,
July 2019 in “Endocrinology” Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.
10 citations,
October 2018 in “Sexual medicine reviews” Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.
5 citations,
June 2022 in “Frontiers in Endocrinology” Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
19 citations,
July 1990 in “Cleveland Clinic journal of medicine” Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
11 citations,
November 2001 in “Journal of Chromatography B: Biomedical Sciences and Applications” Finasteride and analogues separated using LC-MS-MS technique.
24 citations,
January 2013 in “Indian Dermatology Online Journal” Balding people may have higher heart disease risk.
September 2011 in “Urology” Some patients fail bladder function tests due to lower flow rates and higher remaining urine volumes, but the exact reasons for failure are unclear.
January 1994 in “European Journal of Cancer” The European School of Oncology organized various educational events in 1994, highlighting important cancer research findings.
40 citations,
November 2020 in “JAMA Dermatology” Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.
108 citations,
February 2008 in “The Journal of urology/The journal of urology” Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
January 2021 in “ABC Heart Failure & Cardiomyopathy” A 90-year-old man was diagnosed with heart failure due to wild-type transthyretin cardiac amyloidosis.
November 2017 in “International journal of family & community medicine” A man's low testosterone and related symptoms improved after he stopped taking hair loss drugs.
3 citations,
October 2015 in “Human Psychopharmacology-clinical and Experimental” Finasteride doesn't affect sleep spindles in men.
12 citations,
January 2010 in “European Journal of Dermatology” Norgalanthamine from Crinum asiaticum may help hair grow.
47 citations,
April 2003 in “Journal of dermatological science” Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.
13 citations,
January 2007 in “E-journal of Chemistry” Found accurate way to measure finasteride in tablets.