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Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Chitosan-decorated nanoparticles can improve skin delivery and reduce side effects of finasteride.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.

Dutasteride does not seem to change rat spermatogenesis or oxidative stress.

Dutasteride did not change rat spermatogenesis or oxidative stress but needs more research.

Older men with lower levels of available testosterone are more likely to be frail.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Finasteride reduces hair growth in women with hirsutism and works better with electrolysis.

New treatments targeting fibrosis could improve urinary symptoms in BPH.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Dutasteride is more effective than finasteride for hair loss treatment.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Finasteride doesn't affect bone density in male rats.

Finasteride cream reduces hair growth in women with hirsutism, but more research needed.

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

Lovastatin doesn't improve lower urinary tract symptoms treatment.

Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

Finasteride use may increase the risk of male breast cancer.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.