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The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Smaller finasteride particles increase effectiveness in treating hair loss.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Ganoderma lucidum may help treat enlarged prostate in rats.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

The research found that androgens help control blood flow in the rat prostate through a specific binding site.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

α-spinasterol from Melandrium firmum can help reduce prostate enlargement.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.