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Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.

Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.

PRP generally shows better results for hair regrowth than mesotherapy, but more research is needed.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.

Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.

Retinoic acid affects male and female muscle energy use and function differently.

Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Non-drug therapies show promise for hair regrowth but need more research.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

Genes linked to wool fineness in sheep have been identified.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Understanding where cancer cells come from helps create better prevention and treatment methods.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Large prostate links to more hair loss, but age of onset doesn't affect it.

Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.