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Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Finasteride increases hair count and improves hair growth with low risk of side effects.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Ayurvedic herbs may reduce side effects and improve effectiveness of cancer treatments.

Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.

Radiation cystitis patients need better monitoring and early treatment due to higher readmission rates.

The dog's skin condition improved after removing a tumor that was causing hormone imbalances.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

COX-2 and Bcl-2 proteins are involved in Lichen Planus.

Diagnosing oral ulcers can be complex and requires careful examination and follow-up.

Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.

Eating a lot of soy might lower the chance of early hair loss in men likely to get it.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Human scalp hair follicles have PGE2 and its receptors, which might affect hair growth.

PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.

Docetaxel is safe and works well for older people with cancer, with manageable side effects.

After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Androgens and other hormones affect hair growth and skin conditions like acne.

Nearly half of the classification tools in the National Institute of Health and Clinical Excellence's Clinical Knowledge Summaries might not effectively guide management for general practitioners.

Over 65% of people in the United Arab Emirates have undetected vitamin D deficiency, causing symptoms often mistaken for stress or migraines.

Male pattern hair loss may have evolved to promote younger fathers for offspring health and survival, encouraging monogamy and paternal nurturing.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.