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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Method detects finasteride in plasma at very low concentrations.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Targeting colon cancer stem cells might lead to better treatment results.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

PGD2 stops hair growth and is higher in bald men with AGA.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

Some medicinal plants can help heal wounds and may lead to new treatments.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.