research Finasteride for Prostatic Disease: An Updated and Comprehensive Review
Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
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research Highly Efficient Nucleophilic Addition of Alkyl Grignard Reagents to 17-Ketosteroids in the Presence of Cerium(III) Chloride: Synthesis of 17α-Propyl-17β-Hydroxy-4-Androsten-3-One, an Androgen Receptor Antagonist
Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.
research Homology Modeling of 5-Alpha-Reductase 2 Using Available Experimental Data
Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
research Doxazosin and Finasteride Alone or in Combination: The PREDICT Study
Doxazosin alone or combined with finasteride improves prostate symptoms better than finasteride alone, without extra benefits.
research Effect of Finasteride and/or Terazosin on Serum PSA: Results of VA Cooperative Study #359
Finasteride reduces PSA levels, terazosin doesn't affect them, and tracking prostate cancer in patients taking finasteride could be difficult.
research Scientific Evaluation of a Unani Pharmacopoeia-Based Formulation on BPH in Animal Model
The Unani Pharmacopoeia-Based Formulation significantly improved symptoms of enlarged prostate in rats.
research Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides and Their Effect on 5α-Reductase Isoform 2, Androgen Receptor, and Androgen-Dependent Glands
New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.
research Trends in 5-Alpha Reductase Inhibitor Use Before and After the Food and Drug Administration Safety Warning
Prescriptions for 5-alpha reductase inhibitors dropped significantly after the FDA's safety warning, especially for men with benign prostatic hyperplasia.
research Intervention in Prostate Cancer: Slight Advantages for Radical Prostatectomy
Men with early balding may have a higher risk of prostate issues, and surgery for prostate cancer has a slight survival benefit over radiation.
research Baldness In Young Men Could Be A Risk Factor For BPH
Early balding may be a sign of future prostate problems.
research Non-Invasive Diagnosis of Prostate Cancer from Body Fluids Using a Panel of Tumor Suppressor Genes
Blood tests for tumor cells could improve prostate cancer diagnosis and treatment; hair loss severity linked to a gene affecting prostate conditions.
research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia
Large prostate patients more likely to have hair loss.
research The Beneficial Effects of Pumpkin (Cucurbita Pepo L.) Seed Oil for Men's Health
Pumpkin seed oil may improve prostate health, bladder control, and hair growth in men.
research Prostatic Cystic Hyperplasia in a Young Dog: Case Report
A young dog with an enlarged prostate and cysts improved significantly after treatment and surgery.
research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Effects of Castration on Benign Prostatic Hyperplasia
Castration significantly reduces prostate size and BPH symptoms.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research Impact of Anti-Androgen Therapies on COVID-19 Susceptibility: A Case-Control Study in Male Population from Two COVID-19 Regional Centers of Lombardy, Italy
Men taking 5-alpha reductase inhibitors for prostate issues may be less likely to experience severe COVID-19, but it doesn't prevent ICU admission or death.
research Clinical Use of 5α-Reductase Inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research Sexual, Physical, And Overall Adverse Effects In Patients Treated With 5α-Reductase Inhibitors: A Systematic Review And Meta-Analysis
Medications for hair loss and prostate issues can significantly increase the risk of sexual side effects and other negative symptoms.
research Can Long-Term LUTS/BPH Pharmacological Treatment Alter the Outcomes of Surgical Intervention?
Long-term medication for enlarged prostate might not clearly affect the timing or outcomes of later surgery.
research Saw Palmetto
Saw palmetto can help with prostate issues and may promote hair growth.
research New 5α-Reductase Inhibitors: In Vitro and In Vivo Effects
Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.
research 5α-Reductase Inhibitors, Antiviral and Anti-Tumor Activities of Some Steroidal Cyanopyridinone Derivatives
Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
research Cyclohex-1-Ene Carboxylic Acids: Synthesis and Biological Evaluation of Novel Inhibitors of Human 5α Reductase
Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.
research Determination of the Potency of a Novel Saw Palmetto Supercritical CO2 Extract for 5α-Reductase Isoform II Inhibition Using a Cell-Free In Vitro Test System
The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.
research Comparison of Clinical Efficacy of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors
Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.
research Clinics in Diagnostic Imaging: A 55-Year-Old Man with Benign Prostatic Hyperplasia and Extraperitoneal Bladder Perforation
A bladder rupture from prostate treatment was healed with catheterization and antibiotics.
research Chronic Exposure of 5-Alpha Reductase Inhibitor in Young Male Rats Induces Metabolic Disturbance and Depressive-Like Behaviors
Long-term use of a drug for hair loss and prostate issues can cause metabolic problems and depression-like behavior in young male rats.
research Association of Frailty Index with Clinical Benign Prostatic Hyperplasia Progression and Serious Adverse Events: The MTOPS Trial
Frailer men have a higher risk of worsening prostate problems and serious health events needing hospital care.