research Mind the Gender Gap: Does Prolactin Exert Gender and Site-Specific Effects on the Human Hair Follicle?
Prolactin may affect hair growth differently based on gender and scalp area.
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research Basics of Androgen Synthesis and Action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research 5α-Reductase Inhibitors in Androgenetic Alopecia
Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
research Reversible Decreases of Fertility in Male Sprague-Dawley Rats Treated Orally with Finasteride, a 5α-Reductase Inhibitor
Finasteride temporarily lowers male rat fertility without affecting libido.
research The Inhibitory Effect of Scutellaria Baicalensis Extract and Its Active Compound, Baicalin, on the Translocation of the Androgen Receptor with Implications for Preventing Androgenetic Alopecia
Scutellaria baicalensis extract and baicalin may help prevent hair loss.
research Enhancement of Percutaneous Absorption of Finasteride by Cosolvents, Cosurfactant, and Surfactants
Transcutol P best increases Finasteride absorption for hair loss treatment.
research 5α-Reductase Type 1 Inhibition of Oryza Sativa Bran Extract Prepared by Supercritical Carbon Dioxide Fluid
Rice bran extract might help prevent hair loss.
research Alopecia: Unapproved Treatments or Indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research The Modern Management of Hirsutism
Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.
research Androgenic and Anti-Androgenic Effects of Progesterone Derivatives with Different Halogens as Substituents at the C-6 Position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Protective Effect of DA-9401 in Finasteride-Induced Apoptosis in Rat Testis: Inositol Requiring Kinase 1 and c-Jun N-Terminal Kinase Pathway
DA-9401 helps protect rat testis from finasteride damage.
research Value of Hormonal Levels in Patients with Male Androgenetic Alopecia Treated with Finasteride: Better Response in Patients Under 26 Years Old
Finasteride works better for hair loss in patients 26 or younger.
research Does Finasteride Have a Preventive Effect on Chronic Bacterial Prostatitis? Pilot Study Using an Animal Model
Finasteride may help prevent chronic bacterial prostatitis, with better results when combined with antibiotics.
research 3,3-Diphenylpentane Skeleton as a Steroid Skeleton Substitute: Novel Inhibitors of Human 5α-Reductase 1
A new compound effectively inhibits human 5α-reductase 1.
research Utilizing the Hair Follicle to Dissect the Regulation and Autocrine/Paracrine Activities of Prolactin in Humans
Human scalp hair follicles can be used to study how prolactin affects hair growth and cell death.
research Finasteride Inhibits Melanogenesis Through Regulation of the Adenylate Cyclase in Melanocytes and Melanoma Cells
Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
A new non-invasive method can analyze skin mRNA to understand skin diseases better.
research Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist?
Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.
research 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
research Post-Finasteride Syndrome – Does It Really Exist?
Post-finasteride syndrome's existence is uncertain; more research needed.
research Nanoemulgel for Efficient Topical Delivery of Finasteride Against Androgenic Alopecia
Nanoemulgel improves hair growth and quality using finasteride without irritation.
research Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms: The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III
Saw palmetto may improve urinary symptoms with fewer sexual side effects compared to some medications.
research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women
The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.
research Mechanism of Androgenic Alopecia: Addressing Speculations Through Empirical Evidence
Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
research The Effects of Oral 5-Alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in a Rat Model
Oral finasteride and dutasteride may negatively affect erectile function in rats.
research Male-Pattern Baldness, Common Latent Viruses, and Microcompetition
Common latent viruses might contribute to male-pattern baldness by disrupting cell processes that normally suppress hair loss-related proteins.
research Regional Dermatology: Hair and Nail Biology, Hair Loss Conditions, and Dermatological Issues of the Mouth and Genital Regions
The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.